K788-7228 Screening compound: 2-[(2E)-3-(2,6-dichlorophenyl)prop-2-enamido]acetic acid

K788-7228 Screening compound: 2-[(2E)-3-(2,6-dichlorophenyl)prop-2-enamido]acetic acid
K788-7228 Screening compound: 2-[(2E)-3-(2,6-dichlorophenyl)prop-2-enamido]acetic acid alternative view

Chemical Structure Depiction of ChemDiv screening compound K788-7228
2-[(2E)-3-(2,6-dichlorophenyl)prop-2-enamido]acetic acid

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K788-7228

Molecular Formula

C11H9Cl2NO3 (C11 H9 Cl2 NO3)

Compound Name

2-[(2E)-3-(2,6-dichlorophenyl)prop-2-enamido]acetic acid

IUPAC name

2-[(2E)-3-(26-dichlorophenyl)prop-2-enamido]acetic acid

SMILES

OC(CNC(/C=C/c(c(Cl)ccc1)c1Cl)=O)=O

InChI

InChI=1S/C11H9Cl2NO3/c12-8-2-1-3-9(13)7(8)4-5-10(15)14-6-11(16)17/h1-5H,6H2,(H,14,15)(H,16,17)

InChI Key

PIJCLRWELWGNPO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11646789

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

274.1

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

1.103

Distribution Coefficient, logD

-2.532

Water Solubility, LogSw

-2.10

Polar Surface Area

53.094

Acid Dissociation Constant (pKa)

3.76

Base Dissociation Constant (pKb)

-0.45

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

9.10

K788-7228 in Drug Discovery

Included in Screening Libraries

Dark Chemical Matter Library (18430 compounds)

KRAS-Targeted Library (16000 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Epitranscriptome Focused Small Molecule Library (20952 compounds)

Included in 1.7M Stock Database

Structure:
  • Pool
Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Congenital
  • Metabolic
Targets:
  • Kinases
Mechanism of action:
  • Epigenetic

References: we are preparing a list of scientific research reports with K788-7228 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K788-7228?
Check Price and Availability of K788-7228, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K788-7228 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K788-7228
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K788-7228
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K788-7228 available by request