K832-3474 Screening compound: methyl 8-oxo-9-(2,3,4-trimethoxyphenyl)-4H,5H,6H,7H,8H,9H-[1,2,4]triazolo[3,2-b]quinazoline-2-carboxylate

K832-3474 Screening compound: methyl 8-oxo-9-(2,3,4-trimethoxyphenyl)-4H,5H,6H,7H,8H,9H-[1,2,4]triazolo[3,2-b]quinazoline-2-carboxylate
K832-3474 Screening compound: methyl 8-oxo-9-(2,3,4-trimethoxyphenyl)-4H,5H,6H,7H,8H,9H-[1,2,4]triazolo[3,2-b]quinazoline-2-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound K832-3474
methyl 8-oxo-9-(2,3,4-trimethoxyphenyl)-4H,5H,6H,7H,8H,9H-[1,2,4]triazolo[3,2-b]quinazoline-2-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K832-3474

Molecular Formula

C20H22N4O6 (C20 H22 N4 O6)

Compound Name

methyl 8-oxo-9-(2,3,4-trimethoxyphenyl)-4H,5H,6H,7H,8H,9H-[1,2,4]triazolo[3,2-b]quinazoline-2-carboxylate

IUPAC name

methyl 8-oxo-9-(234-trimethoxyphenyl)-4H5H6H7H8H9H-[124]triazolo[32-b]quinazoline-2-carboxylate

SMILES

COC(c1nn(C(c(ccc(OC)c2OC)c2OC)C(C(CCC2)=O)=C2N2)c2n1)=O

InChI

InChI=1S/C20H22N4O6/c1-27-13-9-8-10(16(28-2)17(13)29-3)15-14-11(6-5-7-12(14)25)21-20-22-18(19(26)30-4)23-24(15)20/h8-9,15H,5-7H2,1-4H3,(H,21,22,23)/t15-/m0/s1

InChI Key

YKOVKSMBUPWZQV-HNNXBMFYSA-N

MDL Number (MFCD)

MFCD05033236

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

414.42

Hydrogen Bond Acceptors Count

10.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

10

Partition Coefficient, logP

2.201

Distribution Coefficient, logD

1.505

Water Solubility, LogSw

-3.00

Polar Surface Area

94.855

Acid Dissociation Constant (pKa)

6.80

Base Dissociation Constant (pKb)

-4.58

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

40.00

K832-3474 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

KRAS-Targeted Library (16000 compounds)

Protein-Protein Interaction Library (218420 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Beyond the Flatland Library sp3 enriched (92988 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • Kinases
  • Kinases
Mechanism of action:
  • PPI modulators
Structure:
  • Cyclic compounds

References: we are preparing a list of scientific research reports with K832-3474 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K832-3474?
Check Price and Availability of K832-3474, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K832-3474 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K832-3474
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K832-3474
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K832-3474 available by request