K832-3543 Screening compound: 5-(4-iodophenyl)-7-(4-methylphenyl)-4H,5H,6H,7H-[1,2,3,4]tetrazolo[1,5-a]pyrimidine

K832-3543 Screening compound: 5-(4-iodophenyl)-7-(4-methylphenyl)-4H,5H,6H,7H-[1,2,3,4]tetrazolo[1,5-a]pyrimidine
K832-3543 Screening compound: 5-(4-iodophenyl)-7-(4-methylphenyl)-4H,5H,6H,7H-[1,2,3,4]tetrazolo[1,5-a]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound K832-3543
5-(4-iodophenyl)-7-(4-methylphenyl)-4H,5H,6H,7H-[1,2,3,4]tetrazolo[1,5-a]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K832-3543

Molecular Formula

C17H16IN5 (C17 H16 IN5)

Compound Name

5-(4-iodophenyl)-7-(4-methylphenyl)-4H,5H,6H,7H-[1,2,3,4]tetrazolo[1,5-a]pyrimidine

IUPAC name

(5S7R)-5-(4-iodophenyl)-7-(4-methylphenyl)-4H5H6H7H-[1234]tetrazolo[15-a]pyrimidine

SMILES

Cc1ccc([C@H](C2)n3nnnc3N[C@H]2c(cc2)ccc2I)cc1

InChI

InChI=1S/C17H16IN5/c1-11-2-4-13(5-3-11)16-10-15(12-6-8-14(18)9-7-12)19-17-20-21-22-23(16)17/h2-9,15-16H,10H2,1H3,(H,19,20,22)/t15-,16-/m1/s1

InChI Key

YGAHZMYLSZWGCT-HZPDHXFCSA-N

MDL Number (MFCD)

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

417.25

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.699

Distribution Coefficient, logD

4.699

Water Solubility, LogSw

-4.30

Polar Surface Area

53.546

Acid Dissociation Constant (pKa)

15.23

Base Dissociation Constant (pKb)

-0.77

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

23.50

K832-3543 in Drug Discovery

Included in Screening Libraries

Autophagy-Targeted Library (4564 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K832-3543 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K832-3543?
Check Price and Availability of K832-3543, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K832-3543 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K832-3543
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K832-3543
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K832-3543 available by request