K832-3792 Screening compound: 2-methoxy-4-[7-(2-thienyl)-7,12-dihydro-6H-chromeno[4,3-d][1,2,4]triazolo[1,5-a]pyrimidin-6-yl]phenyl methyl ether

K832-3792 Screening compound: 2-methoxy-4-[7-(2-thienyl)-7,12-dihydro-6H-chromeno[4,3-d][1,2,4]triazolo[1,5-a]pyrimidin-6-yl]phenyl methyl ether
K832-3792 Screening compound: 2-methoxy-4-[7-(2-thienyl)-7,12-dihydro-6H-chromeno[4,3-d][1,2,4]triazolo[1,5-a]pyrimidin-6-yl]phenyl methyl ether alternative view

Chemical Structure Depiction of ChemDiv screening compound K832-3792
2-methoxy-4-[7-(2-thienyl)-7,12-dihydro-6H-chromeno[4,3-d][1,2,4]triazolo[1,5-a]pyrimidin-6-yl]phenyl methyl ether

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K832-3792

Molecular Formula

C24H20N4O3S (C24 H20 N4 O3 S)

Compound Name

2-methoxy-4-[7-(2-thienyl)-7,12-dihydro-6H-chromeno[4,3-d][1,2,4]triazolo[1,5-a]pyrimidin-6-yl]phenyl methyl ether

IUPAC name

9-(34-dimethoxyphenyl)-11-(thiophen-2-yl)-8-oxa-12131517-tetraazatetracyclo[8.7.0.0^{27}.0^{1216}]heptadeca-1(10)2(7)351315-hexaene

SMILES

COc(ccc(C1Oc(cccc2)c2C2=C1C(c1cccs1)n1ncnc1N2)c1)c1OC

InChI

InChI=1S/C24H20N4O3S/c1-29-17-10-9-14(12-18(17)30-2)23-20-21(15-6-3-4-7-16(15)31-23)27-24-25-13-26-28(24)22(20)19-8-5-11-32-19/h3-13,22-23H,1-2H3,(H,25,26,27)

InChI Key

HGNUEJHNYAKQGS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03692286

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.51

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.129

Distribution Coefficient, logD

4.128

Water Solubility, LogSw

-4.42

Polar Surface Area

61.886

Acid Dissociation Constant (pKa)

10.83

Base Dissociation Constant (pKb)

-1.25

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

16.70

K832-3792 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K832-3792 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K832-3792?
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What is the minimum amount of K832-3792 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K832-3792
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K832-3792
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K832-3792 available by request