K832-4197 Screening compound: 4-(5-bromo-2-fluorophenyl)-2-(4-methylphenyl)-1,4-dihydropyrimido[1,2-a][1,3]benzimidazole

K832-4197 Screening compound: 4-(5-bromo-2-fluorophenyl)-2-(4-methylphenyl)-1,4-dihydropyrimido[1,2-a][1,3]benzimidazole
K832-4197 Screening compound: 4-(5-bromo-2-fluorophenyl)-2-(4-methylphenyl)-1,4-dihydropyrimido[1,2-a][1,3]benzimidazole alternative view

Chemical Structure Depiction of ChemDiv screening compound K832-4197
4-(5-bromo-2-fluorophenyl)-2-(4-methylphenyl)-1,4-dihydropyrimido[1,2-a][1,3]benzimidazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K832-4197

Molecular Formula

C23H17BrFN3 (C23 H17 BrFN3)

Compound Name

4-(5-bromo-2-fluorophenyl)-2-(4-methylphenyl)-1,4-dihydropyrimido[1,2-a][1,3]benzimidazole

IUPAC name

13-(5-bromo-2-fluorophenyl)-11-(4-methylphenyl)-1810-triazatricyclo[7.4.0.0^{27}]trideca-2(7)35811-pentaene

SMILES

Cc(cc1)ccc1C(N1)=CC(c(cc(cc2)Br)c2F)n2c1nc1c2cccc1

InChI

InChI=1S/C23H17BrFN3/c1-14-6-8-15(9-7-14)20-13-22(17-12-16(24)10-11-18(17)25)28-21-5-3-2-4-19(21)26-23(28)27-20/h2-13,22H,1H3,(H,26,27)/t22-/m0/s1

InChI Key

UMHCHSRXBMBLCA-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD15110194

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

434.31

Hydrogen Bond Acceptors Count

1.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

6.938

Distribution Coefficient, logD

6.938

Water Solubility, LogSw

-6.00

Polar Surface Area

24.644

Acid Dissociation Constant (pKa)

11.61

Base Dissociation Constant (pKb)

0.71

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

8.70

K832-4197 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K832-4197 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K832-4197?
Check Price and Availability of K832-4197, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K832-4197 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K832-4197
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K832-4197
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K832-4197 available by request