K832-4200 Screening compound: 4-(5-bromo-2-fluorophenyl)-2-(3-bromophenyl)-1,4-dihydropyrimido[1,2-a][1,3]benzimidazole

K832-4200 Screening compound: 4-(5-bromo-2-fluorophenyl)-2-(3-bromophenyl)-1,4-dihydropyrimido[1,2-a][1,3]benzimidazole
K832-4200 Screening compound: 4-(5-bromo-2-fluorophenyl)-2-(3-bromophenyl)-1,4-dihydropyrimido[1,2-a][1,3]benzimidazole alternative view

Chemical Structure Depiction of ChemDiv screening compound K832-4200
4-(5-bromo-2-fluorophenyl)-2-(3-bromophenyl)-1,4-dihydropyrimido[1,2-a][1,3]benzimidazole

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K832-4200

Molecular Formula

C22H14Br2FN3 (C22 H14 Br2 FN3)

Compound Name

4-(5-bromo-2-fluorophenyl)-2-(3-bromophenyl)-1,4-dihydropyrimido[1,2-a][1,3]benzimidazole

IUPAC name

13-(5-bromo-2-fluorophenyl)-11-(3-bromophenyl)-1810-triazatricyclo[7.4.0.0^{27}]trideca-2(7)35811-pentaene

SMILES

Fc(cc1)c(C(C=C(c2cc(Br)ccc2)N2)n3c2nc2c3cccc2)cc1Br

InChI

InChI=1S/C22H14Br2FN3/c23-14-5-3-4-13(10-14)19-12-21(16-11-15(24)8-9-17(16)25)28-20-7-2-1-6-18(20)26-22(28)27-19/h1-12,21H,(H,26,27)/t21-/m0/s1

InChI Key

VKQVJBDMOAMGPX-NRFANRHFSA-N

MDL Number (MFCD)

MFCD15110196

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

499.18

Hydrogen Bond Acceptors Count

1.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

2.00

Number of Nitrogen and Oxygen Atoms

3

Partition Coefficient, logP

7.337

Distribution Coefficient, logD

7.337

Water Solubility, LogSw

-6.52

Polar Surface Area

24.644

Acid Dissociation Constant (pKa)

10.81

Base Dissociation Constant (pKb)

0.71

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

4.50

K832-4200 in Drug Discovery

Included in Screening Libraries

KRAS-Targeted Library (16000 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with K832-4200 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K832-4200?
Check Price and Availability of K832-4200, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K832-4200 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K832-4200
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K832-4200
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K832-4200 available by request