K832-4231 Screening compound: 7-[4-(difluoromethoxy)-3-methoxyphenyl]-5-(4-fluorophenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidine

K832-4231 Screening compound: 7-[4-(difluoromethoxy)-3-methoxyphenyl]-5-(4-fluorophenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidine
K832-4231 Screening compound: 7-[4-(difluoromethoxy)-3-methoxyphenyl]-5-(4-fluorophenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidine alternative view

Chemical Structure Depiction of ChemDiv screening compound K832-4231
7-[4-(difluoromethoxy)-3-methoxyphenyl]-5-(4-fluorophenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K832-4231

Molecular Formula

C19H15F3N4O2 (C19 H15 F3 N4 O2)

Compound Name

7-[4-(difluoromethoxy)-3-methoxyphenyl]-5-(4-fluorophenyl)-4H,7H-[1,2,4]triazolo[1,5-a]pyrimidine

IUPAC name

7-[4-(difluoromethoxy)-3-methoxyphenyl]-5-(4-fluorophenyl)-4H7H-[124]triazolo[15-a]pyrimidine

SMILES

COc(cc(C1n2ncnc2NC(c(cc2)ccc2F)=C1)cc1)c1OC(F)F

InChI

InChI=1S/C19H15F3N4O2/c1-27-17-8-12(4-7-16(17)28-18(21)22)15-9-14(11-2-5-13(20)6-3-11)25-19-23-10-24-26(15)19/h2-10,15,18H,1H3,(H,23,24,25)/t15-/m1/s1

InChI Key

OREMINVHTPWURO-OAHLLOKOSA-N

MDL Number (MFCD)

MFCD05028419

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

388.35

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.549

Distribution Coefficient, logD

3.540

Water Solubility, LogSw

-3.76

Polar Surface Area

52.922

Acid Dissociation Constant (pKa)

9.07

Base Dissociation Constant (pKb)

-1.11

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

15.80

K832-4231 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin

References: we are preparing a list of scientific research reports with K832-4231 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K832-4231?
Check Price and Availability of K832-4231, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K832-4231 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K832-4231
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K832-4231
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K832-4231 available by request