K892-0210 Screening compound: 2-{5-methyl-4-oxo-6-[4-(pyridin-2-yl)piperazine-1-carbonyl]-3H,4H-thieno[2,3-d]pyrimidin-3-yl}-N-[3-(trifluoromethyl)phenyl]acetamide

K892-0210 Screening compound: 2-{5-methyl-4-oxo-6-[4-(pyridin-2-yl)piperazine-1-carbonyl]-3H,4H-thieno[2,3-d]pyrimidin-3-yl}-N-[3-(trifluoromethyl)phenyl]acetamide
K892-0210 Screening compound: 2-{5-methyl-4-oxo-6-[4-(pyridin-2-yl)piperazine-1-carbonyl]-3H,4H-thieno[2,3-d]pyrimidin-3-yl}-N-[3-(trifluoromethyl)phenyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K892-0210
2-{5-methyl-4-oxo-6-[4-(pyridin-2-yl)piperazine-1-carbonyl]-3H,4H-thieno[2,3-d]pyrimidin-3-yl}-N-[3-(trifluoromethyl)phenyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K892-0210

Molecular Formula

C26H23F3N6O3S (C26 H23 F3 N6 O3 S)

Compound Name

2-{5-methyl-4-oxo-6-[4-(pyridin-2-yl)piperazine-1-carbonyl]-3H,4H-thieno[2,3-d]pyrimidin-3-yl}-N-[3-(trifluoromethyl)phenyl]acetamide

IUPAC name

2-{5-methyl-4-oxo-6-[4-(pyridin-2-yl)piperazine-1-carbonyl]-3H4H-thieno[23-d]pyrimidin-3-yl}-N-[3-(trifluoromethyl)phenyl]acetamide

SMILES

Cc1c(C(N(CC2)CCN2c2ncccc2)=O)sc(N=CN2CC(Nc3cc(C(F)(F)F)ccc3)=O)c1C2=O

InChI

InChI=1S/C26H23F3N6O3S/c1-16-21-23(39-22(16)25(38)34-11-9-33(10-12-34)19-7-2-3-8-30-19)31-15-35(24(21)37)14-20(36)32-18-6-4-5-17(13-18)26(27,28)29/h2-8,13,15H,9-12,14H2,1H3,(H,32,36)

InChI Key

FCBKKMVRTDWCRF-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15111228

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

556.57

Hydrogen Bond Acceptors Count

8.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

3.933

Distribution Coefficient, logD

3.924

Water Solubility, LogSw

-4.16

Polar Surface Area

77.811

Acid Dissociation Constant (pKa)

10.53

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.90

K892-0210 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Nucleic Acid Ligands (8311 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K892-0210 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K892-0210?
Check Price and Availability of K892-0210, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K892-0210 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K892-0210
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K892-0210
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K892-0210 available by request