K893-0167 Screening compound: 6-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}-2,3-dihydro-1,3-benzoxazol-2-one

K893-0167 Screening compound: 6-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}-2,3-dihydro-1,3-benzoxazol-2-one
K893-0167 Screening compound: 6-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}-2,3-dihydro-1,3-benzoxazol-2-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K893-0167
6-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}-2,3-dihydro-1,3-benzoxazol-2-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K893-0167

Molecular Formula

C18H19N3O5S (C18 H19 N3 O5 S)

Compound Name

6-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}-2,3-dihydro-1,3-benzoxazol-2-one

IUPAC name

6-{[4-(4-methoxyphenyl)piperazin-1-yl]sulfonyl}-23-dihydro-13-benzoxazol-2-one

SMILES

COc(cc1)ccc1N(CC1)CCN1S(c(cc1)cc(O2)c1NC2=O)(=O)=O

InChI

InChI=1S/C18H19N3O5S/c1-25-14-4-2-13(3-5-14)20-8-10-21(11-9-20)27(23,24)15-6-7-16-17(12-15)26-18(22)19-16/h2-7,12H,8-11H2,1H3,(H,19,22)

InChI Key

NLOMYWLSJLQZBC-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD05030828

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

389.43

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.447

Distribution Coefficient, logD

2.414

Water Solubility, LogSw

-3.07

Polar Surface Area

76.171

Acid Dissociation Constant (pKa)

8.49

Base Dissociation Constant (pKb)

3.05

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.80

K893-0167 in Drug Discovery

Included in Screening Libraries

Anti-Aging Library (44940 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

KRAS-Targeted Library (16000 compounds)

Purinergic Library (3321 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Metabolic
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Cardiovascular
  • Metabolic
Mechanism of action:
  • Epigenetic
  • Receptor's ligands
Targets:
  • Kinases
  • GPCR
  • Ion Channels

References: we are preparing a list of scientific research reports with K893-0167 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K893-0167?
Check Price and Availability of K893-0167, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K893-0167 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K893-0167
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K893-0167
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K893-0167 available by request