K906-0267 Screening compound: N~1~-(2,5-dimethylphenyl)-3-(3,5-dioxo-4-azatricyclo[5.2.1.0~2,6~]dec-8-en-4-yl)propanamide

K906-0267 Screening compound: N~1~-(2,5-dimethylphenyl)-3-(3,5-dioxo-4-azatricyclo[5.2.1.0~2,6~]dec-8-en-4-yl)propanamide
K906-0267 Screening compound: N~1~-(2,5-dimethylphenyl)-3-(3,5-dioxo-4-azatricyclo[5.2.1.0~2,6~]dec-8-en-4-yl)propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K906-0267
N~1~-(2,5-dimethylphenyl)-3-(3,5-dioxo-4-azatricyclo[5.2.1.0~2,6~]dec-8-en-4-yl)propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K906-0267

Molecular Formula

C20H22N2O3 (C20 H22 N2 O3)

Compound Name

N~1~-(2,5-dimethylphenyl)-3-(3,5-dioxo-4-azatricyclo[5.2.1.0~2,6~]dec-8-en-4-yl)propanamide

IUPAC name

N-(25-dimethylphenyl)-3-{35-dioxo-4-azatricyclo[5.2.1.0^{26}]dec-8-en-4-yl}propanamide

SMILES

Cc1cc(NC(CCN(C(C2C3C4C=CC2C4)=O)C3=O)=O)c(C)cc1

InChI

InChI=1S/C20H22N2O3/c1-11-3-4-12(2)15(9-11)21-16(23)7-8-22-19(24)17-13-5-6-14(10-13)18(17)20(22)25/h3-6,9,13-14,17-18H,7-8,10H2,1-2H3,(H,21,23)

InChI Key

GFYCKBPNIZYSLA-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD03185765

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

338.41

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

1.525

Distribution Coefficient, logD

1.525

Water Solubility, LogSw

-2.16

Polar Surface Area

52.766

Acid Dissociation Constant (pKa)

12.13

Base Dissociation Constant (pKb)

-1.60

Number of Chiral Centers

4.00

Percent sp3 carbon bonding

45.00

K906-0267 in Drug Discovery

Included in Screening Libraries

Cysteine Proteases Inhibitors Library (7839 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Nervous system
  • Cardiovascular
  • Skin
  • Metabolic
  • Endocrine
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with K906-0267 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K906-0267?
Check Price and Availability of K906-0267, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K906-0267 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K906-0267
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K906-0267
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K906-0267 available by request