K906-4244 Screening compound: N-{[4-(2,3-dihydro-1H-indole-1-carbonyl)phenyl]methyl}-1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide

K906-4244 Screening compound: N-{[4-(2,3-dihydro-1H-indole-1-carbonyl)phenyl]methyl}-1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide
K906-4244 Screening compound: N-{[4-(2,3-dihydro-1H-indole-1-carbonyl)phenyl]methyl}-1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K906-4244
N-{[4-(2,3-dihydro-1H-indole-1-carbonyl)phenyl]methyl}-1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K906-4244

Molecular Formula

C27H27N3O4S (C27 H27 N3 O4 S)

Compound Name

N-{[4-(2,3-dihydro-1H-indole-1-carbonyl)phenyl]methyl}-1,3,3-trimethyl-2-oxo-2,3-dihydro-1H-indole-5-sulfonamide

IUPAC name

N-{[4-(23-dihydro-1H-indole-1-carbonyl)phenyl]methyl}-133-trimethyl-2-oxo-23-dihydro-1H-indole-5-sulfonamide

SMILES

CC(C)(c(cc(cc1)S(NCc(cc2)ccc2C(N(CC2)c3c2cccc3)=O)(=O)=O)c1N1C)C1=O

InChI

InChI=1S/C27H27N3O4S/c1-27(2)22-16-21(12-13-24(22)29(3)26(27)32)35(33,34)28-17-18-8-10-20(11-9-18)25(31)30-15-14-19-6-4-5-7-23(19)30/h4-13,16,28H,14-15,17H2,1-3H3

InChI Key

FAMSOWUYWFPSSR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15113680

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

489.6

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.682

Distribution Coefficient, logD

3.682

Water Solubility, LogSw

-3.91

Polar Surface Area

73.181

Acid Dissociation Constant (pKa)

10.49

Base Dissociation Constant (pKb)

-2.54

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.90

K906-4244 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Hsp90-Targeted Library (11355 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Aurora A-B Kinases Targeted Library (9426 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
  • Cancer
  • Digestive system
  • Male
  • Female
  • Hemic and lymphatic
Targets:
  • GPCR
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with K906-4244 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K906-4244?
Check Price and Availability of K906-4244, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K906-4244 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K906-4244
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K906-4244
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K906-4244 available by request