K915-1257 Screening compound: methyl 4-[4-(4-chlorophenyl)-6-(2-hydroxy-3-methoxyphenyl)-1,2,5,6-tetrahydropyrimidin-2-yl]benzoate

K915-1257 Screening compound: methyl 4-[4-(4-chlorophenyl)-6-(2-hydroxy-3-methoxyphenyl)-1,2,5,6-tetrahydropyrimidin-2-yl]benzoate
K915-1257 Screening compound: methyl 4-[4-(4-chlorophenyl)-6-(2-hydroxy-3-methoxyphenyl)-1,2,5,6-tetrahydropyrimidin-2-yl]benzoate alternative view

Chemical Structure Depiction of ChemDiv screening compound K915-1257
methyl 4-[4-(4-chlorophenyl)-6-(2-hydroxy-3-methoxyphenyl)-1,2,5,6-tetrahydropyrimidin-2-yl]benzoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K915-1257

Molecular Formula

C25H23ClN2O4 (C25 H23 ClN2 O4)

Compound Name

methyl 4-[4-(4-chlorophenyl)-6-(2-hydroxy-3-methoxyphenyl)-1,2,5,6-tetrahydropyrimidin-2-yl]benzoate

IUPAC name

methyl 4-[4-(4-chlorophenyl)-6-(2-hydroxy-3-methoxyphenyl)-1256-tetrahydropyrimidin-2-yl]benzoate

SMILES

COC(c1ccc(C(NC(C2)c(cccc3OC)c3O)N=C2c(cc2)ccc2Cl)cc1)=O

InChI

InChI=1S/C25H23ClN2O4/c1-31-22-5-3-4-19(23(22)29)21-14-20(15-10-12-18(26)13-11-15)27-24(28-21)16-6-8-17(9-7-16)25(30)32-2/h3-13,21,24,28-29H,14H2,1-2H3

InChI Key

URZWBCUASWWWQR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15114298

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.92

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

5.564

Distribution Coefficient, logD

5.525

Water Solubility, LogSw

-5.95

Polar Surface Area

64.897

Acid Dissociation Constant (pKa)

10.27

Base Dissociation Constant (pKb)

1.13

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

20.00

K915-1257 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with K915-1257 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K915-1257?
Check Price and Availability of K915-1257, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K915-1257 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K915-1257
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K915-1257
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K915-1257 available by request