K915-1368 Screening compound: 2-[2-(3-bromo-4-fluorophenyl)-6-(4-ethylphenyl)-2,3,4,5-tetrahydropyrimidin-4-yl]-6-ethoxyphenol

K915-1368 Screening compound: 2-[2-(3-bromo-4-fluorophenyl)-6-(4-ethylphenyl)-2,3,4,5-tetrahydropyrimidin-4-yl]-6-ethoxyphenol
K915-1368 Screening compound: 2-[2-(3-bromo-4-fluorophenyl)-6-(4-ethylphenyl)-2,3,4,5-tetrahydropyrimidin-4-yl]-6-ethoxyphenol alternative view

Chemical Structure Depiction of ChemDiv screening compound K915-1368
2-[2-(3-bromo-4-fluorophenyl)-6-(4-ethylphenyl)-2,3,4,5-tetrahydropyrimidin-4-yl]-6-ethoxyphenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K915-1368

Molecular Formula

C26H26BrFN2O2 (C26 H26 BrFN2 O2)

Compound Name

2-[2-(3-bromo-4-fluorophenyl)-6-(4-ethylphenyl)-2,3,4,5-tetrahydropyrimidin-4-yl]-6-ethoxyphenol

IUPAC name

2-[2-(3-bromo-4-fluorophenyl)-6-(4-ethylphenyl)-2345-tetrahydropyrimidin-4-yl]-6-ethoxyphenol

SMILES

CCc(cc1)ccc1C(C1)=NC(c(cc2)cc(Br)c2F)NC1c(cccc1OCC)c1O

InChI

InChI=1S/C26H26BrFN2O2/c1-3-16-8-10-17(11-9-16)22-15-23(19-6-5-7-24(25(19)31)32-4-2)30-26(29-22)18-12-13-21(28)20(27)14-18/h5-14,23,26,30-31H,3-4,15H2,1-2H3

InChI Key

QCDSILVVDGHFDD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15114372

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

497.41

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.852

Distribution Coefficient, logD

6.568

Water Solubility, LogSw

-5.78

Polar Surface Area

43.303

Acid Dissociation Constant (pKa)

10.55

Base Dissociation Constant (pKb)

7.36

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

26.90

K915-1368 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with K915-1368 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K915-1368?
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What is the minimum amount of K915-1368 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K915-1368
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K915-1368
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K915-1368 available by request