K915-1449 Screening compound: 4-chloro-2-[6-(4-ethoxyphenyl)-2-(2-fluorophenyl)-2,3,4,5-tetrahydropyrimidin-4-yl]phenol

K915-1449 Screening compound: 4-chloro-2-[6-(4-ethoxyphenyl)-2-(2-fluorophenyl)-2,3,4,5-tetrahydropyrimidin-4-yl]phenol
K915-1449 Screening compound: 4-chloro-2-[6-(4-ethoxyphenyl)-2-(2-fluorophenyl)-2,3,4,5-tetrahydropyrimidin-4-yl]phenol alternative view

Chemical Structure Depiction of ChemDiv screening compound K915-1449
4-chloro-2-[6-(4-ethoxyphenyl)-2-(2-fluorophenyl)-2,3,4,5-tetrahydropyrimidin-4-yl]phenol

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K915-1449

Molecular Formula

C24H22ClFN2O2 (C24 H22 ClFN2 O2)

Compound Name

4-chloro-2-[6-(4-ethoxyphenyl)-2-(2-fluorophenyl)-2,3,4,5-tetrahydropyrimidin-4-yl]phenol

IUPAC name

4-chloro-2-[6-(4-ethoxyphenyl)-2-(2-fluorophenyl)-2345-tetrahydropyrimidin-4-yl]phenol

SMILES

CCOc(cc1)ccc1C(C1)=NC(c(cccc2)c2F)NC1c(cc(cc1)Cl)c1O

InChI

InChI=1S/C24H22ClFN2O2/c1-2-30-17-10-7-15(8-11-17)21-14-22(19-13-16(25)9-12-23(19)29)28-24(27-21)18-5-3-4-6-20(18)26/h3-13,22,24,28-29H,2,14H2,1H3

InChI Key

QYYUDNNKBVTBBK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15114427

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

424.9

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

4

Partition Coefficient, logP

6.020

Distribution Coefficient, logD

5.890

Water Solubility, LogSw

-5.93

Polar Surface Area

44.286

Acid Dissociation Constant (pKa)

10.24

Base Dissociation Constant (pKb)

6.94

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

20.80

K915-1449 in Drug Discovery

Included in Screening Libraries

Hsp90-Targeted Library (11355 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system

References: we are preparing a list of scientific research reports with K915-1449 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K915-1449?
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What is the minimum amount of K915-1449 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K915-1449
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K915-1449
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K915-1449 available by request