K937-0264 Screening compound: N-(2,6-difluorophenyl)-2,5-dimethyl-4-{methyl[4-(propan-2-yl)phenyl]amino}thieno[2,3-d]pyrimidine-6-carboxamide

K937-0264 Screening compound: N-(2,6-difluorophenyl)-2,5-dimethyl-4-{methyl[4-(propan-2-yl)phenyl]amino}thieno[2,3-d]pyrimidine-6-carboxamide
K937-0264 Screening compound: N-(2,6-difluorophenyl)-2,5-dimethyl-4-{methyl[4-(propan-2-yl)phenyl]amino}thieno[2,3-d]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K937-0264
N-(2,6-difluorophenyl)-2,5-dimethyl-4-{methyl[4-(propan-2-yl)phenyl]amino}thieno[2,3-d]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K937-0264

Molecular Formula

C25H24F2N4OS (C25 H24 F2 N4 OS)

Compound Name

N-(2,6-difluorophenyl)-2,5-dimethyl-4-{methyl[4-(propan-2-yl)phenyl]amino}thieno[2,3-d]pyrimidine-6-carboxamide

IUPAC name

N-(26-difluorophenyl)-25-dimethyl-4-{methyl[4-(propan-2-yl)phenyl]amino}thieno[23-d]pyrimidine-6-carboxamide

SMILES

CC(C)c(cc1)ccc1N(C)c1c(c(C)c(C(Nc(c(F)ccc2)c2F)=O)s2)c2nc(C)n1

InChI

InChI=1S/C25H24F2N4OS/c1-13(2)16-9-11-17(12-10-16)31(5)23-20-14(3)22(33-25(20)29-15(4)28-23)24(32)30-21-18(26)7-6-8-19(21)27/h6-13H,1-5H3,(H,30,32)

InChI Key

VPBYZGLYJOXSHU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15114694

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

466.55

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.163

Distribution Coefficient, logD

5.544

Water Solubility, LogSw

-5.89

Polar Surface Area

43.329

Acid Dissociation Constant (pKa)

6.90

Base Dissociation Constant (pKb)

5.62

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

24.00

K937-0264 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

New Agro Library (44492 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases
Agro:
  • Agro

References: we are preparing a list of scientific research reports with K937-0264 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K937-0264?
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What is the minimum amount of K937-0264 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K937-0264
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K937-0264
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K937-0264 available by request