K937-0295 Screening compound: N,2,5-trimethyl-N-[4-(propan-2-yl)phenyl]-6-(1,2,3,4-tetrahydroquinoline-1-carbonyl)thieno[2,3-d]pyrimidin-4-amine

K937-0295 Screening compound: N,2,5-trimethyl-N-[4-(propan-2-yl)phenyl]-6-(1,2,3,4-tetrahydroquinoline-1-carbonyl)thieno[2,3-d]pyrimidin-4-amine
K937-0295 Screening compound: N,2,5-trimethyl-N-[4-(propan-2-yl)phenyl]-6-(1,2,3,4-tetrahydroquinoline-1-carbonyl)thieno[2,3-d]pyrimidin-4-amine alternative view

Chemical Structure Depiction of ChemDiv screening compound K937-0295
N,2,5-trimethyl-N-[4-(propan-2-yl)phenyl]-6-(1,2,3,4-tetrahydroquinoline-1-carbonyl)thieno[2,3-d]pyrimidin-4-amine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K937-0295

Molecular Formula

C28H30N4OS (C28 H30 N4 OS)

Compound Name

N,2,5-trimethyl-N-[4-(propan-2-yl)phenyl]-6-(1,2,3,4-tetrahydroquinoline-1-carbonyl)thieno[2,3-d]pyrimidin-4-amine

IUPAC name

N25-trimethyl-N-[4-(propan-2-yl)phenyl]-6-(1234-tetrahydroquinoline-1-carbonyl)thieno[23-d]pyrimidin-4-amine

SMILES

CC(C)c(cc1)ccc1N(C)c1c(c(C)c(C(N(CCC2)c3c2cccc3)=O)s2)c2nc(C)n1

InChI

InChI=1S/C28H30N4OS/c1-17(2)20-12-14-22(15-13-20)31(5)26-24-18(3)25(34-27(24)30-19(4)29-26)28(33)32-16-8-10-21-9-6-7-11-23(21)32/h6-7,9,11-15,17H,8,10,16H2,1-5H3

InChI Key

BBNZUVIEQHDEOE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15114715

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

470.64

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.954

Distribution Coefficient, logD

6.915

Water Solubility, LogSw

-5.96

Polar Surface Area

36.946

Acid Dissociation Constant (pKa)

24.08

Base Dissociation Constant (pKb)

6.36

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

32.10

K937-0295 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K937-0295 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K937-0295?
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What is the minimum amount of K937-0295 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K937-0295
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K937-0295
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K937-0295 available by request