K937-0300 Screening compound: N-[(4-fluorophenyl)methyl]-2,5-dimethyl-4-{methyl[4-(propan-2-yl)phenyl]amino}thieno[2,3-d]pyrimidine-6-carboxamide

K937-0300 Screening compound: N-[(4-fluorophenyl)methyl]-2,5-dimethyl-4-{methyl[4-(propan-2-yl)phenyl]amino}thieno[2,3-d]pyrimidine-6-carboxamide
K937-0300 Screening compound: N-[(4-fluorophenyl)methyl]-2,5-dimethyl-4-{methyl[4-(propan-2-yl)phenyl]amino}thieno[2,3-d]pyrimidine-6-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound K937-0300
N-[(4-fluorophenyl)methyl]-2,5-dimethyl-4-{methyl[4-(propan-2-yl)phenyl]amino}thieno[2,3-d]pyrimidine-6-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K937-0300

Molecular Formula

C26H27FN4OS (C26 H27 FN4 OS)

Compound Name

N-[(4-fluorophenyl)methyl]-2,5-dimethyl-4-{methyl[4-(propan-2-yl)phenyl]amino}thieno[2,3-d]pyrimidine-6-carboxamide

IUPAC name

N-[(4-fluorophenyl)methyl]-25-dimethyl-4-{methyl[4-(propan-2-yl)phenyl]amino}thieno[23-d]pyrimidine-6-carboxamide

SMILES

CC(C)c(cc1)ccc1N(C)c1c(c(C)c(C(NCc(cc2)ccc2F)=O)s2)c2nc(C)n1

InChI

InChI=1S/C26H27FN4OS/c1-15(2)19-8-12-21(13-9-19)31(5)24-22-16(3)23(33-26(22)30-17(4)29-24)25(32)28-14-18-6-10-20(27)11-7-18/h6-13,15H,14H2,1-5H3,(H,28,32)

InChI Key

DYSBMIBFPQSISR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15114718

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

462.59

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

6.129

Distribution Coefficient, logD

5.981

Water Solubility, LogSw

-5.82

Polar Surface Area

46.047

Acid Dissociation Constant (pKa)

10.74

Base Dissociation Constant (pKb)

7.01

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.90

K937-0300 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K937-0300 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K937-0300?
Check Price and Availability of K937-0300, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K937-0300 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K937-0300
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K937-0300
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K937-0300 available by request