K937-0317 Screening compound: ethyl 4-(2,5-dimethyl-4-{methyl[4-(propan-2-yl)phenyl]amino}thieno[2,3-d]pyrimidine-6-carbonyl)piperazine-1-carboxylate

K937-0317 Screening compound: ethyl 4-(2,5-dimethyl-4-{methyl[4-(propan-2-yl)phenyl]amino}thieno[2,3-d]pyrimidine-6-carbonyl)piperazine-1-carboxylate
K937-0317 Screening compound: ethyl 4-(2,5-dimethyl-4-{methyl[4-(propan-2-yl)phenyl]amino}thieno[2,3-d]pyrimidine-6-carbonyl)piperazine-1-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound K937-0317
ethyl 4-(2,5-dimethyl-4-{methyl[4-(propan-2-yl)phenyl]amino}thieno[2,3-d]pyrimidine-6-carbonyl)piperazine-1-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K937-0317

Molecular Formula

C26H33N5O3S (C26 H33 N5 O3 S)

Compound Name

ethyl 4-(2,5-dimethyl-4-{methyl[4-(propan-2-yl)phenyl]amino}thieno[2,3-d]pyrimidine-6-carbonyl)piperazine-1-carboxylate

IUPAC name

ethyl 4-(25-dimethyl-4-{methyl[4-(propan-2-yl)phenyl]amino}thieno[23-d]pyrimidine-6-carbonyl)piperazine-1-carboxylate

SMILES

CCOC(N(CC1)CCN1C(c1c(C)c2c(N(C)c3ccc(C(C)C)cc3)nc(C)nc2s1)=O)=O

InChI

InChI=1S/C26H33N5O3S/c1-7-34-26(33)31-14-12-30(13-15-31)25(32)22-17(4)21-23(27-18(5)28-24(21)35-22)29(6)20-10-8-19(9-11-20)16(2)3/h8-11,16H,7,12-15H2,1-6H3

InChI Key

YEVBFPAHZPEFFU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15114723

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

495.65

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

5.224

Distribution Coefficient, logD

4.709

Water Solubility, LogSw

-5.17

Polar Surface Area

61.062

Acid Dissociation Constant (pKa)

24.08

Base Dissociation Constant (pKb)

7.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

46.20

K937-0317 in Drug Discovery

Included in Screening Libraries

DGK Inhibitors Library (10558 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Hemic and lymphatic
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with K937-0317 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K937-0317?
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What is the minimum amount of K937-0317 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K937-0317
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K937-0317
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K937-0317 available by request