K940-0516 Screening compound: (2E)-1-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-3-phenylprop-2-en-1-one

K940-0516 Screening compound: (2E)-1-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-3-phenylprop-2-en-1-one
K940-0516 Screening compound: (2E)-1-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-3-phenylprop-2-en-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound K940-0516
(2E)-1-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-3-phenylprop-2-en-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

K940-0516

Molecular Formula

C19H19FN2O3S (C19 H19 FN2 O3 S)

Compound Name

(2E)-1-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-3-phenylprop-2-en-1-one

IUPAC name

(2E)-1-[4-(4-fluorobenzenesulfonyl)piperazin-1-yl]-3-phenylprop-2-en-1-one

SMILES

O=C(/C=C/c1ccccc1)N(CC1)CCN1S(c(cc1)ccc1F)(=O)=O

InChI

InChI=1S/C19H19FN2O3S/c20-17-7-9-18(10-8-17)26(24,25)22-14-12-21(13-15-22)19(23)11-6-16-4-2-1-3-5-16/h1-11H,12-15H2

InChI Key

NNXVAJWZJWSQHU-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD07263318

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

374.44

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

2.895

Distribution Coefficient, logD

2.895

Water Solubility, LogSw

-3.31

Polar Surface Area

47.878

Acid Dissociation Constant (pKa)

28.41

Base Dissociation Constant (pKb)

0.11

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

21.10

K940-0516 in Drug Discovery

Included in Screening Libraries

Antimitotic Tubulin Library (17355 compounds)

Human GPCR Annotated Library (5539 compounds)

KRAS-Targeted Library (16000 compounds)

Selective Target Activity Profiling Library (14702 compounds)

ChemoGenomic Annotated Library for Phenotypic Screening (89798 compounds)

Covalent Inhibitors Library (7986 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases
Structure:
  • Cyclic compounds
  • 3D
  • Fragments

References: we are preparing a list of scientific research reports with K940-0516 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound K940-0516?
Check Price and Availability of K940-0516, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of K940-0516 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for K940-0516
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for K940-0516
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of K940-0516 available by request