L008-0375 Screening compound: N-[(4-bromophenyl)methyl]-4-[6-(morpholin-4-yl)pyridazin-3-yl]benzamide

L008-0375 Screening compound: N-[(4-bromophenyl)methyl]-4-[6-(morpholin-4-yl)pyridazin-3-yl]benzamide
L008-0375 Screening compound: N-[(4-bromophenyl)methyl]-4-[6-(morpholin-4-yl)pyridazin-3-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L008-0375
N-[(4-bromophenyl)methyl]-4-[6-(morpholin-4-yl)pyridazin-3-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L008-0375

Molecular Formula

C22H21BrN4O2 (C22 H21 BrN4 O2)

Compound Name

N-[(4-bromophenyl)methyl]-4-[6-(morpholin-4-yl)pyridazin-3-yl]benzamide

IUPAC name

N-[(4-bromophenyl)methyl]-4-[6-(morpholin-4-yl)pyridazin-3-yl]benzamide

SMILES

O=C(c(cc1)ccc1-c(cc1)nnc1N1CCOCC1)NCc(cc1)ccc1Br

InChI

InChI=1S/C22H21BrN4O2/c23-19-7-1-16(2-8-19)15-24-22(28)18-5-3-17(4-6-18)20-9-10-21(26-25-20)27-11-13-29-14-12-27/h1-10H,11-15H2,(H,24,28)

InChI Key

IEVUFRMZGIEMIS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27225969

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.34

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.788

Distribution Coefficient, logD

3.787

Water Solubility, LogSw

-4.10

Polar Surface Area

56.948

Acid Dissociation Constant (pKa)

11.36

Base Dissociation Constant (pKb)

4.07

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

L008-0375 in Drug Discovery

Included in Screening Libraries

PI3K-Targeted Library (17255 compounds)

Akt-Targeted Library (14764 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
Targets:
  • Kinases
  • Kinases

References: we are preparing a list of scientific research reports with L008-0375 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L008-0375?
Check Price and Availability of L008-0375, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L008-0375 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L008-0375
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L008-0375
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L008-0375 available by request