L010-0083 Screening compound: N-[(2-chlorophenyl)methyl]-4-[6-(pyrrolidin-1-yl)pyrimidin-4-yl]benzamide

L010-0083 Screening compound: N-[(2-chlorophenyl)methyl]-4-[6-(pyrrolidin-1-yl)pyrimidin-4-yl]benzamide
L010-0083 Screening compound: N-[(2-chlorophenyl)methyl]-4-[6-(pyrrolidin-1-yl)pyrimidin-4-yl]benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L010-0083
N-[(2-chlorophenyl)methyl]-4-[6-(pyrrolidin-1-yl)pyrimidin-4-yl]benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L010-0083

Molecular Formula

C22H21ClN4O (C22 H21 ClN4 O)

Compound Name

N-[(2-chlorophenyl)methyl]-4-[6-(pyrrolidin-1-yl)pyrimidin-4-yl]benzamide

IUPAC name

N-[(2-chlorophenyl)methyl]-4-[6-(pyrrolidin-1-yl)pyrimidin-4-yl]benzamide

SMILES

O=C(c(cc1)ccc1-c1ncnc(N2CCCC2)c1)NCc(cccc1)c1Cl

InChI

InChI=1S/C22H21ClN4O/c23-19-6-2-1-5-18(19)14-24-22(28)17-9-7-16(8-10-17)20-13-21(26-15-25-20)27-11-3-4-12-27/h1-2,5-10,13,15H,3-4,11-12,14H2,(H,24,28)

InChI Key

FXQLVNCCBTUIQH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27226148

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

392.89

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.057

Distribution Coefficient, logD

5.056

Water Solubility, LogSw

-5.45

Polar Surface Area

47.472

Acid Dissociation Constant (pKa)

11.78

Base Dissociation Constant (pKb)

4.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.70

L010-0083 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with L010-0083 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L010-0083?
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What is the minimum amount of L010-0083 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L010-0083
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L010-0083
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L010-0083 available by request