L010-0392 Screening compound: N-(1,3-benzodioxol-5-ylmethyl)-4-(6-morpholino-4-pyrimidinyl)benzamide

L010-0392 Screening compound: N-(1,3-benzodioxol-5-ylmethyl)-4-(6-morpholino-4-pyrimidinyl)benzamide
L010-0392 Screening compound: N-(1,3-benzodioxol-5-ylmethyl)-4-(6-morpholino-4-pyrimidinyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L010-0392
N-(1,3-benzodioxol-5-ylmethyl)-4-(6-morpholino-4-pyrimidinyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L010-0392

Molecular Formula

C23H22N4O4 (C23 H22 N4 O4)

Compound Name

N-(1,3-benzodioxol-5-ylmethyl)-4-(6-morpholino-4-pyrimidinyl)benzamide

IUPAC name

N-[(2H-13-benzodioxol-5-yl)methyl]-4-[6-(morpholin-4-yl)pyrimidin-4-yl]benzamide

SMILES

O=C(c(cc1)ccc1-c1ncnc(N2CCOCC2)c1)NCc(cc1)cc2c1OCO2

InChI

InChI=1S/C23H22N4O4/c28-23(24-13-16-1-6-20-21(11-16)31-15-30-20)18-4-2-17(3-5-18)19-12-22(26-14-25-19)27-7-9-29-10-8-27/h1-6,11-12,14H,7-10,13,15H2,(H,24,28)

InChI Key

YIPJELHPODWDJL-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD28119826

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

418.45

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.465

Distribution Coefficient, logD

3.464

Water Solubility, LogSw

-3.55

Polar Surface Area

72.130

Acid Dissociation Constant (pKa)

13.29

Base Dissociation Constant (pKb)

4.73

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

26.09

L010-0392 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer

References: we are preparing a list of scientific research reports with L010-0392 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L010-0392?
Check Price and Availability of L010-0392, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L010-0392 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L010-0392
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L010-0392
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L010-0392 available by request