L010-0464 Screening compound: {4-[6-(cyclohexylamino)-4-pyrimidinyl]phenyl}(4-methylpiperidino)methanone

L010-0464 Screening compound: {4-[6-(cyclohexylamino)-4-pyrimidinyl]phenyl}(4-methylpiperidino)methanone
L010-0464 Screening compound: {4-[6-(cyclohexylamino)-4-pyrimidinyl]phenyl}(4-methylpiperidino)methanone alternative view

Chemical Structure Depiction of ChemDiv screening compound L010-0464
{4-[6-(cyclohexylamino)-4-pyrimidinyl]phenyl}(4-methylpiperidino)methanone

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L010-0464

Molecular Formula

C23H30N4O (C23 H30 N4 O)

Compound Name

{4-[6-(cyclohexylamino)-4-pyrimidinyl]phenyl}(4-methylpiperidino)methanone

IUPAC name

N-cyclohexyl-6-[4-(4-methylpiperidine-1-carbonyl)phenyl]pyrimidin-4-amine

SMILES

CC(CC1)CCN1C(c(cc1)ccc1-c1ncnc(NC2CCCCC2)c1)=O

InChI

InChI=1S/C23H30N4O/c1-17-11-13-27(14-12-17)23(28)19-9-7-18(8-10-19)21-15-22(25-16-24-21)26-20-5-3-2-4-6-20/h7-10,15-17,20H,2-6,11-14H2,1H3,(H,24,25,26)

InChI Key

GFWNFASWEATHAW-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27642314

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

378.52

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.803

Distribution Coefficient, logD

4.803

Water Solubility, LogSw

-4.49

Polar Surface Area

46.952

Acid Dissociation Constant (pKa)

20.03

Base Dissociation Constant (pKb)

4.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

52.17

L010-0464 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Cardiovascular Library (22201 compounds)

GPCR Targeted Library (31838 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Cardiovascular
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L010-0464 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L010-0464?
Check Price and Availability of L010-0464, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L010-0464 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L010-0464
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L010-0464
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L010-0464 available by request