L011-0060 Screening compound: 3-[6-(1-pyrrolidinyl)-4-pyrimidinyl]-N~1~-(1,2,3,4-tetrahydro-1-naphthalenyl)benzamide

L011-0060 Screening compound: 3-[6-(1-pyrrolidinyl)-4-pyrimidinyl]-N~1~-(1,2,3,4-tetrahydro-1-naphthalenyl)benzamide
L011-0060 Screening compound: 3-[6-(1-pyrrolidinyl)-4-pyrimidinyl]-N~1~-(1,2,3,4-tetrahydro-1-naphthalenyl)benzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L011-0060
3-[6-(1-pyrrolidinyl)-4-pyrimidinyl]-N~1~-(1,2,3,4-tetrahydro-1-naphthalenyl)benzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L011-0060

Molecular Formula

C25H26N4O (C25 H26 N4 O)

Compound Name

3-[6-(1-pyrrolidinyl)-4-pyrimidinyl]-N~1~-(1,2,3,4-tetrahydro-1-naphthalenyl)benzamide

IUPAC name

n/a

SMILES

O=C(c1cc(-c2ncnc(N3CCCC3)c2)ccc1)NC(CCC1)c2c1cccc2

InChI

InChI=1S/C25H26N4O/c30-25(28-22-12-6-8-18-7-1-2-11-21(18)22)20-10-5-9-19(15-20)23-16-24(27-17-26-23)29-13-3-4-14-29/h1-2,5,7,9-11,15-17,22H,3-4,6,8,12-14H2,(H,28,30)/t22-/m0/s1

InChI Key

YVQVFPYTFKMVAW-QFIPXVFZSA-N

MDL Number (MFCD)

MFCD27226308

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

398.51

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.205

Distribution Coefficient, logD

5.205

Water Solubility, LogSw

-5.40

Polar Surface Area

47.316

Acid Dissociation Constant (pKa)

11.12

Base Dissociation Constant (pKb)

4.10

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

32.00

L011-0060 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

GPCR Targeted Library (31838 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L011-0060 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L011-0060?
Check Price and Availability of L011-0060, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L011-0060 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L011-0060
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L011-0060
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L011-0060 available by request