L018-0226 Screening compound: N-(2,4-difluorophenyl)-1-[5-(1H-pyrrol-1-yl)pyridin-2-yl]piperidine-4-carboxamide

L018-0226 Screening compound: N-(2,4-difluorophenyl)-1-[5-(1H-pyrrol-1-yl)pyridin-2-yl]piperidine-4-carboxamide
L018-0226 Screening compound: N-(2,4-difluorophenyl)-1-[5-(1H-pyrrol-1-yl)pyridin-2-yl]piperidine-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L018-0226
N-(2,4-difluorophenyl)-1-[5-(1H-pyrrol-1-yl)pyridin-2-yl]piperidine-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L018-0226

Molecular Formula

C21H20F2N4O (C21 H20 F2 N4 O)

Compound Name

N-(2,4-difluorophenyl)-1-[5-(1H-pyrrol-1-yl)pyridin-2-yl]piperidine-4-carboxamide

IUPAC name

N-(24-difluorophenyl)-1-[5-(1H-pyrrol-1-yl)pyridin-2-yl]piperidine-4-carboxamide

SMILES

O=C(C(CC1)CCN1c(cc1)ncc1-n1cccc1)Nc(ccc(F)c1)c1F

InChI

InChI=1S/C21H20F2N4O/c22-16-3-5-19(18(23)13-16)25-21(28)15-7-11-27(12-8-15)20-6-4-17(14-24-20)26-9-1-2-10-26/h1-6,9-10,13-15H,7-8,11-12H2,(H,25,28)

InChI Key

STZBKICPJZIQKZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15116400

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

382.41

Hydrogen Bond Acceptors Count

3.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.171

Distribution Coefficient, logD

4.129

Water Solubility, LogSw

-4.03

Polar Surface Area

38.671

Acid Dissociation Constant (pKa)

8.39

Base Dissociation Constant (pKb)

4.68

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

23.80

L018-0226 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Nervous system
  • Cardiovascular
Targets:
  • Ion Channels

References: we are preparing a list of scientific research reports with L018-0226 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L018-0226?
Check Price and Availability of L018-0226, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L018-0226 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L018-0226
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L018-0226
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L018-0226 available by request