L053-0057 Screening compound: N-(3,5-dimethoxyphenyl)-4-(1-ethyl-1H-1,3-benzodiazol-2-yl)piperazine-1-carboxamide

L053-0057 Screening compound: N-(3,5-dimethoxyphenyl)-4-(1-ethyl-1H-1,3-benzodiazol-2-yl)piperazine-1-carboxamide
L053-0057 Screening compound: N-(3,5-dimethoxyphenyl)-4-(1-ethyl-1H-1,3-benzodiazol-2-yl)piperazine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L053-0057
N-(3,5-dimethoxyphenyl)-4-(1-ethyl-1H-1,3-benzodiazol-2-yl)piperazine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L053-0057

Molecular Formula

C22H27N5O3 (C22 H27 N5 O3)

Compound Name

N-(3,5-dimethoxyphenyl)-4-(1-ethyl-1H-1,3-benzodiazol-2-yl)piperazine-1-carboxamide

IUPAC name

N-(35-dimethoxyphenyl)-4-(1-ethyl-1H-13-benzodiazol-2-yl)piperazine-1-carboxamide

SMILES

CCn1c(N(CC2)CCN2C(Nc2cc(OC)cc(OC)c2)=O)nc2c1cccc2

InChI

InChI=1S/C22H27N5O3/c1-4-27-20-8-6-5-7-19(20)24-21(27)25-9-11-26(12-10-25)22(28)23-16-13-17(29-2)15-18(14-16)30-3/h5-8,13-15H,4,9-12H2,1-3H3,(H,23,28)

InChI Key

KNTDCAKDJONCBT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15116758

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

409.49

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

4.000

Distribution Coefficient, logD

3.958

Water Solubility, LogSw

-4.07

Polar Surface Area

53.521

Acid Dissociation Constant (pKa)

12.07

Base Dissociation Constant (pKb)

6.41

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

36.40

L053-0057 in Drug Discovery

Included in Screening Libraries

Angiogenesis library (14822 compounds)

Nucleic Acid Ligands (8311 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Infections
  • Cancer
  • Musculoskeletal
  • Nervous system
  • Hemic and lymphatic
  • Immune system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
Targets:
  • Proteases

References: we are preparing a list of scientific research reports with L053-0057 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L053-0057?
Check Price and Availability of L053-0057, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L053-0057 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L053-0057
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L053-0057
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L053-0057 available by request