L053-0270 Screening compound: ethyl 3-{[4-(1-benzyl-1H-1,3-benzodiazol-2-yl)piperazine-1-carbonyl]amino}propanoate

L053-0270 Screening compound: ethyl 3-{[4-(1-benzyl-1H-1,3-benzodiazol-2-yl)piperazine-1-carbonyl]amino}propanoate
L053-0270 Screening compound: ethyl 3-{[4-(1-benzyl-1H-1,3-benzodiazol-2-yl)piperazine-1-carbonyl]amino}propanoate alternative view

Chemical Structure Depiction of ChemDiv screening compound L053-0270
ethyl 3-{[4-(1-benzyl-1H-1,3-benzodiazol-2-yl)piperazine-1-carbonyl]amino}propanoate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L053-0270

Molecular Formula

C24H29N5O3 (C24 H29 N5 O3)

Compound Name

ethyl 3-{[4-(1-benzyl-1H-1,3-benzodiazol-2-yl)piperazine-1-carbonyl]amino}propanoate

IUPAC name

ethyl 3-{[4-(1-benzyl-1H-13-benzodiazol-2-yl)piperazine-1-carbonyl]amino}propanoate

SMILES

CCOC(CCNC(N(CC1)CCN1c1nc(cccc2)c2n1Cc1ccccc1)=O)=O

InChI

InChI=1S/C24H29N5O3/c1-2-32-22(30)12-13-25-24(31)28-16-14-27(15-17-28)23-26-20-10-6-7-11-21(20)29(23)18-19-8-4-3-5-9-19/h3-11H,2,12-18H2,1H3,(H,25,31)

InChI Key

JBGZKNNONKJAQD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15116904

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

435.53

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

10.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.768

Distribution Coefficient, logD

3.735

Water Solubility, LogSw

-3.79

Polar Surface Area

60.031

Acid Dissociation Constant (pKa)

16.56

Base Dissociation Constant (pKb)

6.30

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

37.50

L053-0270 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

PI3K-Targeted Library (17255 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Male
  • Female
  • Hemic and lymphatic
  • Skin
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Cardiovascular
Targets:
  • Kinases
  • Proteases
  • Ion Channels

References: we are preparing a list of scientific research reports with L053-0270 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L053-0270?
Check Price and Availability of L053-0270, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L053-0270 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L053-0270
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L053-0270
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L053-0270 available by request