L057-0207 Screening compound: 1-(3-chloro-4-fluorophenyl)-3-{[1-(4-methylbenzoyl)-2,3-dihydro-1H-indol-6-yl]methyl}urea

L057-0207 Screening compound: 1-(3-chloro-4-fluorophenyl)-3-{[1-(4-methylbenzoyl)-2,3-dihydro-1H-indol-6-yl]methyl}urea
L057-0207 Screening compound: 1-(3-chloro-4-fluorophenyl)-3-{[1-(4-methylbenzoyl)-2,3-dihydro-1H-indol-6-yl]methyl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L057-0207
1-(3-chloro-4-fluorophenyl)-3-{[1-(4-methylbenzoyl)-2,3-dihydro-1H-indol-6-yl]methyl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L057-0207

Molecular Formula

C24H21ClFN3O2 (C24 H21 ClFN3 O2)

Compound Name

1-(3-chloro-4-fluorophenyl)-3-{[1-(4-methylbenzoyl)-2,3-dihydro-1H-indol-6-yl]methyl}urea

IUPAC name

1-(3-chloro-4-fluorophenyl)-3-{[1-(4-methylbenzoyl)-23-dihydro-1H-indol-6-yl]methyl}urea

SMILES

Cc(cc1)ccc1C(N(CC1)c2c1ccc(CNC(Nc(cc1)cc(Cl)c1F)=O)c2)=O

InChI

InChI=1S/C24H21ClFN3O2/c1-15-2-5-18(6-3-15)23(30)29-11-10-17-7-4-16(12-22(17)29)14-27-24(31)28-19-8-9-21(26)20(25)13-19/h2-9,12-13H,10-11,14H2,1H3,(H2,27,28,31)

InChI Key

SSPZXSZZQAHEDK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27227014

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

437.9

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

5.044

Distribution Coefficient, logD

5.044

Water Solubility, LogSw

-5.27

Polar Surface Area

49.542

Acid Dissociation Constant (pKa)

10.38

Base Dissociation Constant (pKb)

-1.33

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

L057-0207 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L057-0207 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L057-0207?
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What is the minimum amount of L057-0207 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L057-0207
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L057-0207
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L057-0207 available by request