L057-1749 Screening compound: 1-(2,5-difluorophenyl)-3-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-6-yl]methyl}urea

L057-1749 Screening compound: 1-(2,5-difluorophenyl)-3-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-6-yl]methyl}urea
L057-1749 Screening compound: 1-(2,5-difluorophenyl)-3-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-6-yl]methyl}urea alternative view

Chemical Structure Depiction of ChemDiv screening compound L057-1749
1-(2,5-difluorophenyl)-3-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-6-yl]methyl}urea

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L057-1749

Molecular Formula

C24H21F2N3O2 (C24 H21 F2 N3 O2)

Compound Name

1-(2,5-difluorophenyl)-3-{[1-(3-methylbenzoyl)-2,3-dihydro-1H-indol-6-yl]methyl}urea

IUPAC name

1-(25-difluorophenyl)-3-{[1-(3-methylbenzoyl)-23-dihydro-1H-indol-6-yl]methyl}urea

SMILES

Cc1cccc(C(N(CC2)c3c2ccc(CNC(Nc(cc(cc2)F)c2F)=O)c3)=O)c1

InChI

InChI=1S/C24H21F2N3O2/c1-15-3-2-4-18(11-15)23(30)29-10-9-17-6-5-16(12-22(17)29)14-27-24(31)28-21-13-19(25)7-8-20(21)26/h2-8,11-13H,9-10,14H2,1H3,(H2,27,28,31)

InChI Key

YIXAMTXRRAQAKG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27227285

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

421.45

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.346

Distribution Coefficient, logD

4.345

Water Solubility, LogSw

-4.27

Polar Surface Area

48.845

Acid Dissociation Constant (pKa)

10.29

Base Dissociation Constant (pKb)

-0.99

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

16.70

L057-1749 in Drug Discovery

Included in Screening Libraries

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

References: we are preparing a list of scientific research reports with L057-1749 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L057-1749?
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What is the minimum amount of L057-1749 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L057-1749
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L057-1749
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L057-1749 available by request