L061-0543 Screening compound: 5-{[(cyclobutylcarbonyl)amino]methyl}-N~2~-phenyl-1,3,4-thiadiazole-2-carboxamide

L061-0543 Screening compound: 5-{[(cyclobutylcarbonyl)amino]methyl}-N~2~-phenyl-1,3,4-thiadiazole-2-carboxamide
L061-0543 Screening compound: 5-{[(cyclobutylcarbonyl)amino]methyl}-N~2~-phenyl-1,3,4-thiadiazole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L061-0543
5-{[(cyclobutylcarbonyl)amino]methyl}-N~2~-phenyl-1,3,4-thiadiazole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L061-0543

Molecular Formula

C15H16N4O2S (C15 H16 N4 O2 S)

Compound Name

5-{[(cyclobutylcarbonyl)amino]methyl}-N~2~-phenyl-1,3,4-thiadiazole-2-carboxamide

IUPAC name

5-[(cyclobutylformamido)methyl]-N-phenyl-134-thiadiazole-2-carboxamide

SMILES

O=C(C1CCC1)NCc1nnc(C(Nc2ccccc2)=O)s1

InChI

InChI=1S/C15H16N4O2S/c20-13(10-5-4-6-10)16-9-12-18-19-15(22-12)14(21)17-11-7-2-1-3-8-11/h1-3,7-8,10H,4-6,9H2,(H,16,20)(H,17,21)

InChI Key

LGGCOWFISLRHTG-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27227828

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

316.38

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

1.119

Distribution Coefficient, logD

1.119

Water Solubility, LogSw

-2.14

Polar Surface Area

72.265

Acid Dissociation Constant (pKa)

11.40

Base Dissociation Constant (pKb)

-0.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.33

L061-0543 in Drug Discovery

Included in Screening Libraries

Antiviral Library (67538 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Soluble Diversity Library (15920 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L061-0543 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L061-0543?
Check Price and Availability of L061-0543, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L061-0543 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L061-0543
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L061-0543
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L061-0543 available by request