L065-0002 Screening compound: 3-{5-[(4-fluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}-N-(3-methoxyphenyl)piperidine-1-carboxamide

L065-0002 Screening compound: 3-{5-[(4-fluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}-N-(3-methoxyphenyl)piperidine-1-carboxamide
L065-0002 Screening compound: 3-{5-[(4-fluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}-N-(3-methoxyphenyl)piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L065-0002
3-{5-[(4-fluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}-N-(3-methoxyphenyl)piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L065-0002

Molecular Formula

C22H22FN5O3S (C22 H22 FN5 O3 S)

Compound Name

3-{5-[(4-fluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}-N-(3-methoxyphenyl)piperidine-1-carboxamide

IUPAC name

3-{5-[(4-fluorophenyl)carbamoyl]-134-thiadiazol-2-yl}-N-(3-methoxyphenyl)piperidine-1-carboxamide

SMILES

COc1cccc(NC(N(CCC2)CC2c2nnc(C(Nc(cc3)ccc3F)=O)s2)=O)c1

InChI

InChI=1S/C22H22FN5O3S/c1-31-18-6-2-5-17(12-18)25-22(30)28-11-3-4-14(13-28)20-26-27-21(32-20)19(29)24-16-9-7-15(23)8-10-16/h2,5-10,12,14H,3-4,11,13H2,1H3,(H,24,29)(H,25,30)/t14-/m0/s1

InChI Key

MORAIAFKCJGCPY-AWEZNQCLSA-N

MDL Number (MFCD)

MFCD15117112

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

455.51

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.644

Distribution Coefficient, logD

3.641

Water Solubility, LogSw

-4.01

Polar Surface Area

79.508

Acid Dissociation Constant (pKa)

9.60

Base Dissociation Constant (pKb)

-1.01

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.30

L065-0002 in Drug Discovery

Included in Screening Libraries

GABA Library (7115 compounds)

Targeted Diversity Library (40567 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L065-0002 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L065-0002?
Check Price and Availability of L065-0002, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L065-0002 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L065-0002
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L065-0002
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L065-0002 available by request