L065-0014 Screening compound: N-(3,5-dimethylphenyl)-3-{5-[(4-fluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}piperidine-1-carboxamide

L065-0014 Screening compound: N-(3,5-dimethylphenyl)-3-{5-[(4-fluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}piperidine-1-carboxamide
L065-0014 Screening compound: N-(3,5-dimethylphenyl)-3-{5-[(4-fluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L065-0014
N-(3,5-dimethylphenyl)-3-{5-[(4-fluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L065-0014

Molecular Formula

C23H24FN5O2S (C23 H24 FN5 O2 S)

Compound Name

N-(3,5-dimethylphenyl)-3-{5-[(4-fluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}piperidine-1-carboxamide

IUPAC name

N-(35-dimethylphenyl)-3-{5-[(4-fluorophenyl)carbamoyl]-134-thiadiazol-2-yl}piperidine-1-carboxamide

SMILES

Cc1cc(NC(N(CCC2)CC2c2nnc(C(Nc(cc3)ccc3F)=O)s2)=O)cc(C)c1

InChI

InChI=1S/C23H24FN5O2S/c1-14-10-15(2)12-19(11-14)26-23(31)29-9-3-4-16(13-29)21-27-28-22(32-21)20(30)25-18-7-5-17(24)6-8-18/h5-8,10-12,16H,3-4,9,13H2,1-2H3,(H,25,30)(H,26,31)/t16-/m0/s1

InChI Key

HFJHYRLPSYQTTR-INIZCTEOSA-N

MDL Number (MFCD)

MFCD15117122

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.270

Distribution Coefficient, logD

4.267

Water Solubility, LogSw

-4.23

Polar Surface Area

71.965

Acid Dissociation Constant (pKa)

9.60

Base Dissociation Constant (pKb)

1.22

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.40

L065-0014 in Drug Discovery

Included in Screening Libraries

GABA Library (7115 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
Targets:
  • GPCR
  • Ion Channels
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L065-0014 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L065-0014?
Check Price and Availability of L065-0014, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L065-0014 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L065-0014
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L065-0014
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L065-0014 available by request