L065-0052 Screening compound: 3-{5-[(4-fluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}-N-(2-phenylethyl)piperidine-1-carboxamide

L065-0052 Screening compound: 3-{5-[(4-fluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}-N-(2-phenylethyl)piperidine-1-carboxamide
L065-0052 Screening compound: 3-{5-[(4-fluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}-N-(2-phenylethyl)piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L065-0052
3-{5-[(4-fluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}-N-(2-phenylethyl)piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L065-0052

Molecular Formula

C23H24FN5O2S (C23 H24 FN5 O2 S)

Compound Name

3-{5-[(4-fluorophenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}-N-(2-phenylethyl)piperidine-1-carboxamide

IUPAC name

3-{5-[(4-fluorophenyl)carbamoyl]-134-thiadiazol-2-yl}-N-(2-phenylethyl)piperidine-1-carboxamide

SMILES

O=C(c1nnc(C(CCC2)CN2C(NCCc2ccccc2)=O)s1)Nc(cc1)ccc1F

InChI

InChI=1S/C23H24FN5O2S/c24-18-8-10-19(11-9-18)26-20(30)22-28-27-21(32-22)17-7-4-14-29(15-17)23(31)25-13-12-16-5-2-1-3-6-16/h1-3,5-6,8-11,17H,4,7,12-15H2,(H,25,31)(H,26,30)/t17-/m0/s1

InChI Key

IZUXXFVAFZKKIR-KRWDZBQOSA-N

MDL Number (MFCD)

MFCD15117149

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

453.54

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.621

Distribution Coefficient, logD

3.619

Water Solubility, LogSw

-3.77

Polar Surface Area

73.128

Acid Dissociation Constant (pKa)

9.60

Base Dissociation Constant (pKb)

0.53

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

30.40

L065-0052 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Infections
  • Immune system
  • animal
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L065-0052 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L065-0052?
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What is the minimum amount of L065-0052 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L065-0052
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L065-0052
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L065-0052 available by request