L065-0128 Screening compound: N-(2,4-difluorophenyl)-3-{5-[(4-methoxyphenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}piperidine-1-carboxamide

L065-0128 Screening compound: N-(2,4-difluorophenyl)-3-{5-[(4-methoxyphenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}piperidine-1-carboxamide
L065-0128 Screening compound: N-(2,4-difluorophenyl)-3-{5-[(4-methoxyphenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}piperidine-1-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L065-0128
N-(2,4-difluorophenyl)-3-{5-[(4-methoxyphenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}piperidine-1-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L065-0128

Molecular Formula

C22H21F2N5O3S (C22 H21 F2 N5 O3 S)

Compound Name

N-(2,4-difluorophenyl)-3-{5-[(4-methoxyphenyl)carbamoyl]-1,3,4-thiadiazol-2-yl}piperidine-1-carboxamide

IUPAC name

N-(24-difluorophenyl)-3-{5-[(4-methoxyphenyl)carbamoyl]-134-thiadiazol-2-yl}piperidine-1-carboxamide

SMILES

COc(cc1)ccc1NC(c1nnc(C(CCC2)CN2C(Nc(ccc(F)c2)c2F)=O)s1)=O

InChI

InChI=1S/C22H21F2N5O3S/c1-32-16-7-5-15(6-8-16)25-19(30)21-28-27-20(33-21)13-3-2-10-29(12-13)22(31)26-18-9-4-14(23)11-17(18)24/h4-9,11,13H,2-3,10,12H2,1H3,(H,25,30)(H,26,31)/t13-/m0/s1

InChI Key

RSVYXJZCTXNIMA-ZDUSSCGKSA-N

MDL Number (MFCD)

MFCD15117194

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

473.5

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

3.842

Distribution Coefficient, logD

3.842

Water Solubility, LogSw

-4.03

Polar Surface Area

78.811

Acid Dissociation Constant (pKa)

10.25

Base Dissociation Constant (pKb)

-0.34

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

27.30

References: we are preparing a list of scientific research reports with L065-0128 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L065-0128?
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What is the minimum amount of L065-0128 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L065-0128
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L065-0128
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L065-0128 available by request