L075-0161 Screening compound: 2-[1-(1H-indole-2-carbonyl)piperidin-4-yl]-N-[3-(4-methylpiperazin-1-yl)propyl]acetamide

L075-0161 Screening compound: 2-[1-(1H-indole-2-carbonyl)piperidin-4-yl]-N-[3-(4-methylpiperazin-1-yl)propyl]acetamide
L075-0161 Screening compound: 2-[1-(1H-indole-2-carbonyl)piperidin-4-yl]-N-[3-(4-methylpiperazin-1-yl)propyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L075-0161
2-[1-(1H-indole-2-carbonyl)piperidin-4-yl]-N-[3-(4-methylpiperazin-1-yl)propyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L075-0161

Molecular Formula

C24H35N5O2 (C24 H35 N5 O2)

Compound Name

2-[1-(1H-indole-2-carbonyl)piperidin-4-yl]-N-[3-(4-methylpiperazin-1-yl)propyl]acetamide

IUPAC name

2-[1-(1H-indole-2-carbonyl)piperidin-4-yl]-N-[3-(4-methylpiperazin-1-yl)propyl]acetamide

SMILES

CN1CCN(CCCNC(CC(CC2)CCN2C(c2cc(cccc3)c3[nH]2)=O)=O)CC1

InChI

InChI=1S/C24H35N5O2/c1-27-13-15-28(16-14-27)10-4-9-25-23(30)17-19-7-11-29(12-8-19)24(31)22-18-20-5-2-3-6-21(20)26-22/h2-3,5-6,18-19,26H,4,7-17H2,1H3,(H,25,30)

InChI Key

SYARQJBOALJUEX-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27228833

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

425.57

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

1.771

Distribution Coefficient, logD

0.567

Water Solubility, LogSw

-2.60

Polar Surface Area

57.736

Acid Dissociation Constant (pKa)

15.07

Base Dissociation Constant (pKb)

8.58

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

58.30

L075-0161 in Drug Discovery

Included in Screening Libraries

GPCR Targeted Library (31838 compounds)

Peptidomimetic Library (37031 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L075-0161 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L075-0161?
Check Price and Availability of L075-0161, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L075-0161 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L075-0161
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L075-0161
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L075-0161 available by request