L075-0888 Screening compound: 2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]-N-[(4-methylphenyl)methyl]acetamide

L075-0888 Screening compound: 2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]-N-[(4-methylphenyl)methyl]acetamide
L075-0888 Screening compound: 2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]-N-[(4-methylphenyl)methyl]acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L075-0888
2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]-N-[(4-methylphenyl)methyl]acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L075-0888

Molecular Formula

C24H26ClN3O2 (C24 H26 ClN3 O2)

Compound Name

2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]-N-[(4-methylphenyl)methyl]acetamide

IUPAC name

2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]-N-[(4-methylphenyl)methyl]acetamide

SMILES

Cc1ccc(CNC(CC(CC2)CCN2C(c2cc(cc(cc3)Cl)c3[nH]2)=O)=O)cc1

InChI

InChI=1S/C24H26ClN3O2/c1-16-2-4-18(5-3-16)15-26-23(29)12-17-8-10-28(11-9-17)24(30)22-14-19-13-20(25)6-7-21(19)27-22/h2-7,13-14,17,27H,8-12,15H2,1H3,(H,26,29)

InChI Key

QQHPCMMPZXRZMD-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15117850

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

423.94

Hydrogen Bond Acceptors Count

4.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

4.814

Distribution Coefficient, logD

4.814

Water Solubility, LogSw

-4.79

Polar Surface Area

50.436

Acid Dissociation Constant (pKa)

12.82

Base Dissociation Constant (pKb)

-0.13

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L075-0888 in Drug Discovery

Included in Screening Libraries

Proline Kinase Library (2105 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Nervous system
  • Male
  • Female
  • Endocrine
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L075-0888 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L075-0888?
Check Price and Availability of L075-0888, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L075-0888 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L075-0888
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L075-0888
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L075-0888 available by request