L075-1138 Screening compound: 2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-1-one

L075-1138 Screening compound: 2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-1-one
L075-1138 Screening compound: 2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-1-one alternative view

Chemical Structure Depiction of ChemDiv screening compound L075-1138
2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-1-one

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L075-1138

Molecular Formula

C26H30ClN5O2 (C26 H30 ClN5 O2)

Compound Name

2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-1-one

IUPAC name

2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]-1-[4-(pyridin-2-yl)piperazin-1-yl]propan-1-one

SMILES

CC(C(CC1)CCN1C(c1cc(cc(cc2)Cl)c2[nH]1)=O)C(N(CC1)CCN1c1ncccc1)=O

InChI

InChI=1S/C26H30ClN5O2/c1-18(25(33)32-14-12-30(13-15-32)24-4-2-3-9-28-24)19-7-10-31(11-8-19)26(34)23-17-20-16-21(27)5-6-22(20)29-23/h2-6,9,16-19,29H,7-8,10-15H2,1H3/t18-/m0/s1

InChI Key

OFMDAEGCEHEKPG-SFHVURJKSA-N

MDL Number (MFCD)

MFCD27228993

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

480.01

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

6.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.419

Distribution Coefficient, logD

4.411

Water Solubility, LogSw

-4.45

Polar Surface Area

54.656

Acid Dissociation Constant (pKa)

15.07

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

42.30

L075-1138 in Drug Discovery

Included in Screening Libraries

Anti-Inflammatory Library (24602 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

CNS Targets (44014 compounds)

Protein Kinases Inhibitors Library (36801 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Immune system
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L075-1138 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L075-1138?
Check Price and Availability of L075-1138, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L075-1138 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L075-1138
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L075-1138
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L075-1138 available by request