L075-1236 Screening compound: N-[3-(azepan-1-yl)butyl]-2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]propanamide

L075-1236 Screening compound: N-[3-(azepan-1-yl)butyl]-2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]propanamide
L075-1236 Screening compound: N-[3-(azepan-1-yl)butyl]-2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]propanamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L075-1236
N-[3-(azepan-1-yl)butyl]-2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]propanamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L075-1236

Molecular Formula

C27H39ClN4O2 (C27 H39 ClN4 O2)

Compound Name

N-[3-(azepan-1-yl)butyl]-2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]propanamide

IUPAC name

N-[3-(azepan-1-yl)butyl]-2-[1-(5-chloro-1H-indole-2-carbonyl)piperidin-4-yl]propanamide

SMILES

CC(CCNC(C(C)C(CC1)CCN1C(c1cc(cc(cc2)Cl)c2[nH]1)=O)=O)N1CCCCCC1

InChI

InChI=1S/C27H39ClN4O2/c1-19(31-13-5-3-4-6-14-31)9-12-29-26(33)20(2)21-10-15-32(16-11-21)27(34)25-18-22-17-23(28)7-8-24(22)30-25/h7-8,17-21,30H,3-6,9-16H2,1-2H3,(H,29,33)

InChI Key

TWTILTKUAIHAJJ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27229025

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

487.09

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

4.539

Distribution Coefficient, logD

1.549

Water Solubility, LogSw

-4.58

Polar Surface Area

54.462

Acid Dissociation Constant (pKa)

14.41

Base Dissociation Constant (pKb)

10.39

Number of Chiral Centers

2.00

Percent sp3 carbon bonding

63.00

L075-1236 in Drug Discovery

Included in Screening Libraries

3D-Diversity Natural-Product-Like Library (18102 compounds)

CNS Targets (44014 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Serine Proteases Inhibitors Library (32732 compounds)

Ion Channels Focused Library (26372 compounds)

Included in 1.7M Stock Database

Structure:
  • 3D
  • Mimetics
Therapeutical areas:
  • Nervous system
  • Infections
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Respiratory tract
  • Male
  • Female
  • Cardiovascular
  • Skin
  • Metabolic
  • Immune system
  • Nervous system
  • Cardiovascular
Mechanism of action:
  • PPI modulators
  • PPI modulators
Targets:
  • Proteases
  • Ion Channels

References: we are preparing a list of scientific research reports with L075-1236 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L075-1236?
Check Price and Availability of L075-1236, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L075-1236 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L075-1236
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L075-1236
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L075-1236 available by request