L076-1168 Screening compound: N-(2,4-difluorophenyl)-5-[1-(4-methoxybenzoyl)piperidin-4-yl]-1,3,4-thiadiazole-2-carboxamide

L076-1168 Screening compound: N-(2,4-difluorophenyl)-5-[1-(4-methoxybenzoyl)piperidin-4-yl]-1,3,4-thiadiazole-2-carboxamide
L076-1168 Screening compound: N-(2,4-difluorophenyl)-5-[1-(4-methoxybenzoyl)piperidin-4-yl]-1,3,4-thiadiazole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L076-1168
N-(2,4-difluorophenyl)-5-[1-(4-methoxybenzoyl)piperidin-4-yl]-1,3,4-thiadiazole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L076-1168

Molecular Formula

C22H20F2N4O3S (C22 H20 F2 N4 O3 S)

Compound Name

N-(2,4-difluorophenyl)-5-[1-(4-methoxybenzoyl)piperidin-4-yl]-1,3,4-thiadiazole-2-carboxamide

IUPAC name

N-(24-difluorophenyl)-5-[1-(4-methoxybenzoyl)piperidin-4-yl]-134-thiadiazole-2-carboxamide

SMILES

COc(cc1)ccc1C(N(CC1)CCC1c1nnc(C(Nc(ccc(F)c2)c2F)=O)s1)=O

InChI

InChI=1S/C22H20F2N4O3S/c1-31-16-5-2-14(3-6-16)22(30)28-10-8-13(9-11-28)20-26-27-21(32-20)19(29)25-18-7-4-15(23)12-17(18)24/h2-7,12-13H,8-11H2,1H3,(H,25,29)

InChI Key

NRLDCRJVRCIDKN-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27229185

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

458.49

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

3.211

Distribution Coefficient, logD

3.040

Water Solubility, LogSw

-3.52

Polar Surface Area

70.056

Acid Dissociation Constant (pKa)

7.72

Base Dissociation Constant (pKb)

-2.76

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

27.30

L076-1168 in Drug Discovery

Included in Screening Libraries

Protein Kinases Inhibitors Library (36801 compounds)

Antibacterial Compounds Library (13827 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Nervous system
  • Hemic and lymphatic
  • Cardiovascular
  • Infections
  • Immune system
  • animal
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L076-1168 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L076-1168?
Check Price and Availability of L076-1168, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L076-1168 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L076-1168
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L076-1168
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L076-1168 available by request