L083-0877 Screening compound: 5-{[4-(cyclohexylcarbamoyl)phenoxy]methyl}-N-(2-methylphenyl)-1,3,4-thiadiazole-2-carboxamide

L083-0877 Screening compound: 5-{[4-(cyclohexylcarbamoyl)phenoxy]methyl}-N-(2-methylphenyl)-1,3,4-thiadiazole-2-carboxamide
L083-0877 Screening compound: 5-{[4-(cyclohexylcarbamoyl)phenoxy]methyl}-N-(2-methylphenyl)-1,3,4-thiadiazole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L083-0877
5-{[4-(cyclohexylcarbamoyl)phenoxy]methyl}-N-(2-methylphenyl)-1,3,4-thiadiazole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L083-0877

Molecular Formula

C24H26N4O3S (C24 H26 N4 O3 S)

Compound Name

5-{[4-(cyclohexylcarbamoyl)phenoxy]methyl}-N-(2-methylphenyl)-1,3,4-thiadiazole-2-carboxamide

IUPAC name

5-{[4-(cyclohexylcarbamoyl)phenoxy]methyl}-N-(2-methylphenyl)-134-thiadiazole-2-carboxamide

SMILES

Cc(cccc1)c1NC(c1nnc(COc(cc2)ccc2C(NC2CCCCC2)=O)s1)=O

InChI

InChI=1S/C24H26N4O3S/c1-16-7-5-6-10-20(16)26-23(30)24-28-27-21(32-24)15-31-19-13-11-17(12-14-19)22(29)25-18-8-3-2-4-9-18/h5-7,10-14,18H,2-4,8-9,15H2,1H3,(H,25,29)(H,26,30)

InChI Key

KIUJUYRMZUIODH-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15118305

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

450.56

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.102

Distribution Coefficient, logD

4.102

Water Solubility, LogSw

-4.10

Polar Surface Area

77.997

Acid Dissociation Constant (pKa)

11.16

Base Dissociation Constant (pKb)

-1.06

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

33.30

L083-0877 in Drug Discovery

Included in Screening Libraries

GABA Library (7115 compounds)

Regenerative Medicine Focused Library (23016 compounds)

PD-1/L1 Library (498 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Eye
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds
  • Cancer
  • Respiratory tract
  • Male
  • Female
  • Hemic and lymphatic
  • Immune system
Targets:
  • GPCR
  • Ion Channels
  • Others
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L083-0877 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L083-0877?
Check Price and Availability of L083-0877, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L083-0877 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L083-0877
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L083-0877
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L083-0877 available by request