L083-1135 Screening compound: N-(2-fluorophenyl)-5-[(4-{[2-(morpholin-4-yl)ethyl]carbamoyl}phenoxy)methyl]-1,3,4-thiadiazole-2-carboxamide

L083-1135 Screening compound: N-(2-fluorophenyl)-5-[(4-{[2-(morpholin-4-yl)ethyl]carbamoyl}phenoxy)methyl]-1,3,4-thiadiazole-2-carboxamide
L083-1135 Screening compound: N-(2-fluorophenyl)-5-[(4-{[2-(morpholin-4-yl)ethyl]carbamoyl}phenoxy)methyl]-1,3,4-thiadiazole-2-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L083-1135
N-(2-fluorophenyl)-5-[(4-{[2-(morpholin-4-yl)ethyl]carbamoyl}phenoxy)methyl]-1,3,4-thiadiazole-2-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L083-1135

Molecular Formula

C23H24FN5O4S (C23 H24 FN5 O4 S)

Compound Name

N-(2-fluorophenyl)-5-[(4-{[2-(morpholin-4-yl)ethyl]carbamoyl}phenoxy)methyl]-1,3,4-thiadiazole-2-carboxamide

IUPAC name

N-(2-fluorophenyl)-5-[(4-{[2-(morpholin-4-yl)ethyl]carbamoyl}phenoxy)methyl]-134-thiadiazole-2-carboxamide

SMILES

O=C(c1nnc(COc(cc2)ccc2C(NCCN2CCOCC2)=O)s1)Nc(cccc1)c1F

InChI

InChI=1S/C23H24FN5O4S/c24-18-3-1-2-4-19(18)26-22(31)23-28-27-20(34-23)15-33-17-7-5-16(6-8-17)21(30)25-9-10-29-11-13-32-14-12-29/h1-8H,9-15H2,(H,25,30)(H,26,31)

InChI Key

MZMGQTFABGZQLV-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15118334

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

485.54

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

2.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.827

Distribution Coefficient, logD

1.810

Water Solubility, LogSw

-2.42

Polar Surface Area

90.005

Acid Dissociation Constant (pKa)

9.52

Base Dissociation Constant (pKb)

5.92

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.40

L083-1135 in Drug Discovery

Included in Screening Libraries

Anticancer Library (62698 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds

References: we are preparing a list of scientific research reports with L083-1135 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L083-1135?
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What is the minimum amount of L083-1135 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L083-1135
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L083-1135
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L083-1135 available by request