L084-0390 Screening compound: N-{2-[5-(4-{1,4-dioxa-8-azaspiro[4.5]decane-8-carbonyl}phenyl)-1,2,4-oxadiazol-3-yl]ethyl}-N-methylbenzamide

L084-0390 Screening compound: N-{2-[5-(4-{1,4-dioxa-8-azaspiro[4.5]decane-8-carbonyl}phenyl)-1,2,4-oxadiazol-3-yl]ethyl}-N-methylbenzamide
L084-0390 Screening compound: N-{2-[5-(4-{1,4-dioxa-8-azaspiro[4.5]decane-8-carbonyl}phenyl)-1,2,4-oxadiazol-3-yl]ethyl}-N-methylbenzamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L084-0390
N-{2-[5-(4-{1,4-dioxa-8-azaspiro[4.5]decane-8-carbonyl}phenyl)-1,2,4-oxadiazol-3-yl]ethyl}-N-methylbenzamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L084-0390

Molecular Formula

C26H28N4O5 (C26 H28 N4 O5)

Compound Name

N-{2-[5-(4-{1,4-dioxa-8-azaspiro[4.5]decane-8-carbonyl}phenyl)-1,2,4-oxadiazol-3-yl]ethyl}-N-methylbenzamide

IUPAC name

N-{2-[5-(4-{14-dioxa-8-azaspiro[4.5]decane-8-carbonyl}phenyl)-124-oxadiazol-3-yl]ethyl}-N-methylbenzamide

SMILES

CN(CCc1noc(-c(cc2)ccc2C(N(CC2)CCC22OCCO2)=O)n1)C(c1ccccc1)=O

InChI

InChI=1S/C26H28N4O5/c1-29(24(31)20-5-3-2-4-6-20)14-11-22-27-23(35-28-22)19-7-9-21(10-8-19)25(32)30-15-12-26(13-16-30)33-17-18-34-26/h2-10H,11-18H2,1H3

InChI Key

VBMVAQOJJABHQE-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD15118372

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

476.53

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

8.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

1.834

Distribution Coefficient, logD

1.834

Water Solubility, LogSw

-1.92

Polar Surface Area

80.120

Acid Dissociation Constant (pKa)

27.30

Base Dissociation Constant (pKb)

-2.03

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

38.50

L084-0390 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

Lipid Metabolism Library (9174 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
  • Cardiovascular
  • Metabolic
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
  • GPCR
Mechanism of action:
  • Receptor's ligands
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L084-0390 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L084-0390?
Check Price and Availability of L084-0390, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L084-0390 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L084-0390
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L084-0390
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L084-0390 available by request