L090-2143 Screening compound: N-({1-[(4-fluorophenyl)methyl]piperidin-4-yl}methyl)-6-methyl-7-oxo-1-phenyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidine-3-carboxamide

L090-2143 Screening compound: N-({1-[(4-fluorophenyl)methyl]piperidin-4-yl}methyl)-6-methyl-7-oxo-1-phenyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidine-3-carboxamide
L090-2143 Screening compound: N-({1-[(4-fluorophenyl)methyl]piperidin-4-yl}methyl)-6-methyl-7-oxo-1-phenyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidine-3-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L090-2143
N-({1-[(4-fluorophenyl)methyl]piperidin-4-yl}methyl)-6-methyl-7-oxo-1-phenyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidine-3-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L090-2143

Molecular Formula

C26H27FN6O2 (C26 H27 FN6 O2)

Compound Name

N-({1-[(4-fluorophenyl)methyl]piperidin-4-yl}methyl)-6-methyl-7-oxo-1-phenyl-1H,6H,7H-pyrazolo[4,3-d]pyrimidine-3-carboxamide

IUPAC name

N-({1-[(4-fluorophenyl)methyl]piperidin-4-yl}methyl)-6-methyl-7-oxo-1-phenyl-1H6H7H-pyrazolo[43-d]pyrimidine-3-carboxamide

SMILES

CN(C=Nc1c2n(-c3ccccc3)nc1C(NCC1CCN(Cc(cc3)ccc3F)CC1)=O)C2=O

InChI

InChI=1S/C26H27FN6O2/c1-31-17-29-22-23(30-33(24(22)26(31)35)21-5-3-2-4-6-21)25(34)28-15-18-11-13-32(14-12-18)16-19-7-9-20(27)10-8-19/h2-10,17-18H,11-16H2,1H3,(H,28,34)

InChI Key

IGLPXUWQBQZXTR-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27231886

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

474.54

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.077

Distribution Coefficient, logD

0.287

Water Solubility, LogSw

-2.54

Polar Surface Area

66.472

Acid Dissociation Constant (pKa)

11.97

Base Dissociation Constant (pKb)

9.18

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

30.80

L090-2143 in Drug Discovery

Included in Screening Libraries

CNS Targets (44014 compounds)

Adenosine Receptors Targeted Library (19896 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Nervous system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Nervous system
  • Eye
  • Cardiovascular
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L090-2143 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L090-2143?
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What is the minimum amount of L090-2143 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L090-2143
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L090-2143
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L090-2143 available by request