L097-0598 Screening compound: 1-(pyridin-2-yl)-4-[2-(pyridin-4-yl)-1,3-thiazole-4-carbonyl]piperazine

L097-0598 Screening compound: 1-(pyridin-2-yl)-4-[2-(pyridin-4-yl)-1,3-thiazole-4-carbonyl]piperazine
L097-0598 Screening compound: 1-(pyridin-2-yl)-4-[2-(pyridin-4-yl)-1,3-thiazole-4-carbonyl]piperazine alternative view

Chemical Structure Depiction of ChemDiv screening compound L097-0598
1-(pyridin-2-yl)-4-[2-(pyridin-4-yl)-1,3-thiazole-4-carbonyl]piperazine

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L097-0598

Molecular Formula

C18H17N5OS (C18 H17 N5 OS)

Compound Name

1-(pyridin-2-yl)-4-[2-(pyridin-4-yl)-1,3-thiazole-4-carbonyl]piperazine

IUPAC name

1-(pyridin-2-yl)-4-[2-(pyridin-4-yl)-13-thiazole-4-carbonyl]piperazine

SMILES

O=C(c1csc(-c2ccncc2)n1)N(CC1)CCN1c1ncccc1

InChI

InChI=1S/C18H17N5OS/c24-18(15-13-25-17(21-15)14-4-7-19-8-5-14)23-11-9-22(10-12-23)16-3-1-2-6-20-16/h1-8,13H,9-12H2

InChI Key

OVJHIEJOEOEJGT-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27232109

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

351.43

Hydrogen Bond Acceptors Count

5.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

4.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

2.601

Distribution Coefficient, logD

2.592

Water Solubility, LogSw

-2.64

Polar Surface Area

47.821

Acid Dissociation Constant (pKa)

24.77

Base Dissociation Constant (pKb)

5.71

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

22.20

L097-0598 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

GPCR Targeted Library (31838 compounds)

SmartTM Library (51161 compounds)

Targeted Diversity Library (40567 compounds)

Epigenetics Focused Set (26518 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Musculoskeletal
  • Respiratory tract
  • Nervous system
  • Congenital
  • Skin
  • Metabolic
  • Endocrine
Targets:
  • GPCR
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L097-0598 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L097-0598?
Check Price and Availability of L097-0598, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L097-0598 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L097-0598
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L097-0598
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L097-0598 available by request