L103-0705 Screening compound: ethyl 1-{3-[(4-chlorophenyl)methanesulfonyl]quinoxalin-2-yl}piperidine-4-carboxylate

L103-0705 Screening compound: ethyl 1-{3-[(4-chlorophenyl)methanesulfonyl]quinoxalin-2-yl}piperidine-4-carboxylate
L103-0705 Screening compound: ethyl 1-{3-[(4-chlorophenyl)methanesulfonyl]quinoxalin-2-yl}piperidine-4-carboxylate alternative view

Chemical Structure Depiction of ChemDiv screening compound L103-0705
ethyl 1-{3-[(4-chlorophenyl)methanesulfonyl]quinoxalin-2-yl}piperidine-4-carboxylate

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L103-0705

Molecular Formula

C23H24ClN3O4S (C23 H24 ClN3 O4 S)

Compound Name

ethyl 1-{3-[(4-chlorophenyl)methanesulfonyl]quinoxalin-2-yl}piperidine-4-carboxylate

IUPAC name

ethyl 1-{3-[(4-chlorophenyl)methanesulfonyl]quinoxalin-2-yl}piperidine-4-carboxylate

SMILES

CCOC(C(CC1)CCN1c1nc2ccccc2nc1S(Cc(cc1)ccc1Cl)(=O)=O)=O

InChI

InChI=1S/C23H24ClN3O4S/c1-2-31-23(28)17-11-13-27(14-12-17)21-22(26-20-6-4-3-5-19(20)25-21)32(29,30)15-16-7-9-18(24)10-8-16/h3-10,17H,2,11-15H2,1H3

InChI Key

PIPAHSMLQSIZSZ-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD11998017

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

473.98

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

7

Partition Coefficient, logP

4.762

Distribution Coefficient, logD

4.762

Water Solubility, LogSw

-4.85

Polar Surface Area

70.621

Acid Dissociation Constant (pKa)

19.48

Base Dissociation Constant (pKb)

-1.28

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

34.80

L103-0705 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

KRAS-Targeted Library (16000 compounds)

?ysteine Targeted Covalent Library (39471 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
Targets:
  • Kinases

References: we are preparing a list of scientific research reports with L103-0705 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L103-0705?
Check Price and Availability of L103-0705, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L103-0705 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L103-0705
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L103-0705
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L103-0705 available by request