L107-0652 Screening compound: N-(4-butylphenyl)-2-{3-[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-2-oxo-1,2-dihydropyridin-1-yl}acetamide

L107-0652 Screening compound: N-(4-butylphenyl)-2-{3-[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-2-oxo-1,2-dihydropyridin-1-yl}acetamide
L107-0652 Screening compound: N-(4-butylphenyl)-2-{3-[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-2-oxo-1,2-dihydropyridin-1-yl}acetamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L107-0652
N-(4-butylphenyl)-2-{3-[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-2-oxo-1,2-dihydropyridin-1-yl}acetamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L107-0652

Molecular Formula

C27H28N4O5 (C27 H28 N4 O5)

Compound Name

N-(4-butylphenyl)-2-{3-[3-(3,4-dimethoxyphenyl)-1,2,4-oxadiazol-5-yl]-2-oxo-1,2-dihydropyridin-1-yl}acetamide

IUPAC name

N-(4-butylphenyl)-2-{3-[3-(34-dimethoxyphenyl)-124-oxadiazol-5-yl]-2-oxo-12-dihydropyridin-1-yl}acetamide

SMILES

CCCCc(cc1)ccc1NC(CN(C=CC=C1c2nc(-c(cc3)cc(OC)c3OC)no2)C1=O)=O

InChI

InChI=1S/C27H28N4O5/c1-4-5-7-18-9-12-20(13-10-18)28-24(32)17-31-15-6-8-21(27(31)33)26-29-25(30-36-26)19-11-14-22(34-2)23(16-19)35-3/h6,8-16H,4-5,7,17H2,1-3H3,(H,28,32)

InChI Key

WRHBTRIMPWNAJO-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD18202106

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

488.54

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

11.00

Number of Nitrogen and Oxygen Atoms

9

Partition Coefficient, logP

5.146

Distribution Coefficient, logD

5.146

Water Solubility, LogSw

-5.04

Polar Surface Area

85.769

Acid Dissociation Constant (pKa)

12.85

Base Dissociation Constant (pKb)

0.40

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

25.90

L107-0652 in Drug Discovery

Included in Screening Libraries

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

Eccentric PPI Library (11937 compounds)

Protein-Protein Interaction Library (218420 compounds)

Regenerative Medicine Focused Library (23016 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Cyclic compounds
Therapeutical areas:
  • Musculoskeletal
  • Digestive system
  • Hemic and lymphatic
  • Cardiovascular
  • Skin
  • wounds

References: we are preparing a list of scientific research reports with L107-0652 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L107-0652?
Check Price and Availability of L107-0652, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L107-0652 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L107-0652
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L107-0652
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L107-0652 available by request