L120-1049 Screening compound: N-(2-methoxy-5-methylphenyl)-6,6-dimethyl-2-(4-methylphenyl)-3,8-dioxo-2,3,5,6,7,8-hexahydroisoquinoline-4-carboxamide

L120-1049 Screening compound: N-(2-methoxy-5-methylphenyl)-6,6-dimethyl-2-(4-methylphenyl)-3,8-dioxo-2,3,5,6,7,8-hexahydroisoquinoline-4-carboxamide
L120-1049 Screening compound: N-(2-methoxy-5-methylphenyl)-6,6-dimethyl-2-(4-methylphenyl)-3,8-dioxo-2,3,5,6,7,8-hexahydroisoquinoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L120-1049
N-(2-methoxy-5-methylphenyl)-6,6-dimethyl-2-(4-methylphenyl)-3,8-dioxo-2,3,5,6,7,8-hexahydroisoquinoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L120-1049

Molecular Formula

C27H28N2O4 (C27 H28 N2 O4)

Compound Name

N-(2-methoxy-5-methylphenyl)-6,6-dimethyl-2-(4-methylphenyl)-3,8-dioxo-2,3,5,6,7,8-hexahydroisoquinoline-4-carboxamide

IUPAC name

N-(2-methoxy-5-methylphenyl)-66-dimethyl-2-(4-methylphenyl)-38-dioxo-235678-hexahydroisoquinoline-4-carboxamide

SMILES

CC(C)(CC(C1=CN2c3ccc(C)cc3)=C(C(Nc(cc(C)cc3)c3OC)=O)C2=O)CC1=O

InChI

InChI=1S/C27H28N2O4/c1-16-6-9-18(10-7-16)29-15-20-19(13-27(3,4)14-22(20)30)24(26(29)32)25(31)28-21-12-17(2)8-11-23(21)33-5/h6-12,15H,13-14H2,1-5H3,(H,28,31)

InChI Key

BTHSTPPKJSFWRK-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27233792

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

444.53

Hydrogen Bond Acceptors Count

7.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

5.00

Number of Nitrogen and Oxygen Atoms

6

Partition Coefficient, logP

3.716

Distribution Coefficient, logD

3.500

Water Solubility, LogSw

-4.09

Polar Surface Area

59.218

Acid Dissociation Constant (pKa)

7.59

Base Dissociation Constant (pKb)

-1.70

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.60

L120-1049 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L120-1049 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L120-1049?
Check Price and Availability of L120-1049, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L120-1049 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L120-1049
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L120-1049
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L120-1049 available by request