L120-1231 Screening compound: 6,6-dimethyl-3,8-dioxo-2-phenyl-N-(3,4,5-trimethoxyphenyl)-2,3,5,6,7,8-hexahydroisoquinoline-4-carboxamide

L120-1231 Screening compound: 6,6-dimethyl-3,8-dioxo-2-phenyl-N-(3,4,5-trimethoxyphenyl)-2,3,5,6,7,8-hexahydroisoquinoline-4-carboxamide
L120-1231 Screening compound: 6,6-dimethyl-3,8-dioxo-2-phenyl-N-(3,4,5-trimethoxyphenyl)-2,3,5,6,7,8-hexahydroisoquinoline-4-carboxamide alternative view

Chemical Structure Depiction of ChemDiv screening compound L120-1231
6,6-dimethyl-3,8-dioxo-2-phenyl-N-(3,4,5-trimethoxyphenyl)-2,3,5,6,7,8-hexahydroisoquinoline-4-carboxamide

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L120-1231

Molecular Formula

C27H28N2O6 (C27 H28 N2 O6)

Compound Name

6,6-dimethyl-3,8-dioxo-2-phenyl-N-(3,4,5-trimethoxyphenyl)-2,3,5,6,7,8-hexahydroisoquinoline-4-carboxamide

IUPAC name

66-dimethyl-38-dioxo-2-phenyl-N-(345-trimethoxyphenyl)-235678-hexahydroisoquinoline-4-carboxamide

SMILES

CC(C)(CC(C1=CN2c3ccccc3)=C(C(Nc(cc3OC)cc(OC)c3OC)=O)C2=O)CC1=O

InChI

InChI=1S/C27H28N2O6/c1-27(2)13-18-19(20(30)14-27)15-29(17-9-7-6-8-10-17)26(32)23(18)25(31)28-16-11-21(33-3)24(35-5)22(12-16)34-4/h6-12,15H,13-14H2,1-5H3,(H,28,31)

InChI Key

TULZZPCZSAXRSM-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27233862

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

476.53

Hydrogen Bond Acceptors Count

9.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

7.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

2.516

Distribution Coefficient, logD

1.629

Water Solubility, LogSw

-3.06

Polar Surface Area

75.264

Acid Dissociation Constant (pKa)

6.57

Base Dissociation Constant (pKb)

-1.51

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.60

L120-1231 in Drug Discovery

Included in Screening Libraries

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L120-1231 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L120-1231?
Check Price and Availability of L120-1231, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L120-1231 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L120-1231
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L120-1231
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L120-1231 available by request