L120-1249 Screening compound: 6,6-dimethyl-2-phenyl-4-(1,2,3,4-tetrahydroquinoline-1-carbonyl)-2,3,5,6,7,8-hexahydroisoquinoline-3,8-dione

L120-1249 Screening compound: 6,6-dimethyl-2-phenyl-4-(1,2,3,4-tetrahydroquinoline-1-carbonyl)-2,3,5,6,7,8-hexahydroisoquinoline-3,8-dione
L120-1249 Screening compound: 6,6-dimethyl-2-phenyl-4-(1,2,3,4-tetrahydroquinoline-1-carbonyl)-2,3,5,6,7,8-hexahydroisoquinoline-3,8-dione alternative view

Chemical Structure Depiction of ChemDiv screening compound L120-1249
6,6-dimethyl-2-phenyl-4-(1,2,3,4-tetrahydroquinoline-1-carbonyl)-2,3,5,6,7,8-hexahydroisoquinoline-3,8-dione

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L120-1249

Molecular Formula

C27H26N2O3 (C27 H26 N2 O3)

Compound Name

6,6-dimethyl-2-phenyl-4-(1,2,3,4-tetrahydroquinoline-1-carbonyl)-2,3,5,6,7,8-hexahydroisoquinoline-3,8-dione

IUPAC name

66-dimethyl-2-phenyl-4-(1234-tetrahydroquinoline-1-carbonyl)-235678-hexahydroisoquinoline-38-dione

SMILES

CC(C)(CC(C1=CN2c3ccccc3)=C(C(N(CCC3)c4c3cccc4)=O)C2=O)CC1=O

InChI

InChI=1S/C27H26N2O3/c1-27(2)15-20-21(23(30)16-27)17-29(19-11-4-3-5-12-19)26(32)24(20)25(31)28-14-8-10-18-9-6-7-13-22(18)28/h3-7,9,11-13,17H,8,10,14-16H2,1-2H3

InChI Key

JVRUUOLKINFHRS-UHFFFAOYSA-N

MDL Number (MFCD)

MFCD27233874

Chemical and Physical Properties

Saltdata

n/a

Molecular Weight

426.52

Hydrogen Bond Acceptors Count

6.00

Hydrogen Bond Donors Count

0.00

Rotatable Bond Count

3.00

Number of Nitrogen and Oxygen Atoms

5

Partition Coefficient, logP

3.697

Distribution Coefficient, logD

3.697

Water Solubility, LogSw

-3.98

Polar Surface Area

44.507

Acid Dissociation Constant (pKa)

24.31

Base Dissociation Constant (pKb)

-2.46

Number of Chiral Centers

0.00

Percent sp3 carbon bonding

29.60

L120-1249 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Antiviral HBV Library (10007 compounds)

Antiviral Library (67538 compounds)

300k Representative Compounds Library (Bemis-Murcko Clustering Algorithm) (286253 compounds)

C-Met Library (15277 compounds)

Included in 1.7M Stock Database

Therapeutical areas:
  • Antiviral
  • Infections
  • Immune system
  • Antiviral
  • Infections
  • Immune system
  • Cancer
  • Digestive system
  • Respiratory tract
  • Otorhinolaryngologic
  • Endocrine
Targets:
  • Kinases
Mechanism of action:
  • Receptor's ligands

References: we are preparing a list of scientific research reports with L120-1249 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L120-1249?
Check Price and Availability of L120-1249, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L120-1249 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L120-1249
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L120-1249
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L120-1249 available by request