L127-0557 Screening compound: N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-N-[2-(PIPERAZINOSULFONYL)ETHYL]-5,6,7,8-TETRAHYDRO-2-NAPHTHALENESULFONAMIDE

L127-0557 Screening compound: N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-N-[2-(PIPERAZINOSULFONYL)ETHYL]-5,6,7,8-TETRAHYDRO-2-NAPHTHALENESULFONAMIDE
L127-0557 Screening compound: N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-N-[2-(PIPERAZINOSULFONYL)ETHYL]-5,6,7,8-TETRAHYDRO-2-NAPHTHALENESULFONAMIDE alternative view

Chemical Structure Depiction of ChemDiv screening compound L127-0557
N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-N-[2-(PIPERAZINOSULFONYL)ETHYL]-5,6,7,8-TETRAHYDRO-2-NAPHTHALENESULFONAMIDE

Available from 1 mg

Formats:

  • Glass Vials (4ml Glass Vials VWR #97047-678)
  • 96-tube racks (Matrix #4247 96-well 1.4ml sealed with capmats, empty cols 1 & 12, 100uL of 10mM)

Shiptime: 1 week worldwide delivery in most cases

Compound Identifiers

ChemDiv Compound ID

L127-0557

Molecular Formula

C23H38N4O4S2 (C23 H38 N4 O4 S2)

Compound Name

N-[(1-ETHYL-2-PYRROLIDINYL)METHYL]-N-[2-(PIPERAZINOSULFONYL)ETHYL]-5,6,7,8-TETRAHYDRO-2-NAPHTHALENESULFONAMIDE

IUPAC name

N-[(1-ethylpyrrolidin-2-yl)methyl]-N-[2-(piperazine-1-sulfonyl)ethyl]-5678-tetrahydronaphthalene-2-sulfonamide

SMILES

CCN1C(CN(CCS(N2CCNCC2)(=O)=O)S(c2cc(CCCC3)c3cc2)(=O)=O)CCC1

InChI

InChI=1S/C23H38N4O4S2/c1-2-25-13-5-8-22(25)19-27(16-17-32(28,29)26-14-11-24-12-15-26)33(30,31)23-10-9-20-6-3-4-7-21(20)18-23/h9-10,18,22,24H,2-8,11-17,19H2,1H3/t22-/m1/s1

InChI Key

LJOFQSPIALGGIM-JOCHJYFZSA-N

MDL Number (MFCD)

MFCD15119076

Chemical and Physical Properties

Saltdata

CF3COOH

Molecular Weight

498.71

Hydrogen Bond Acceptors Count

12.00

Hydrogen Bond Donors Count

1.00

Rotatable Bond Count

9.00

Number of Nitrogen and Oxygen Atoms

8

Partition Coefficient, logP

1.776

Distribution Coefficient, logD

1.432

Water Solubility, LogSw

-2.48

Polar Surface Area

78.985

Acid Dissociation Constant (pKa)

22.14

Base Dissociation Constant (pKb)

7.48

Number of Chiral Centers

1.00

Percent sp3 carbon bonding

73.91

L127-0557 in Drug Discovery

Included in Screening Libraries

3D-Pharmacophore Based Diversity Library (49813 compounds)

Nonpeptide Peptidomimetics PPI Library (18997 compounds)

Protein-Protein Interaction Library (218420 compounds)

Included in 1.7M Stock Database

Mechanism of action:
  • PPI modulators
  • PPI modulators
Structure:
  • Mimetics

References: we are preparing a list of scientific research reports with L127-0557 chemical compound. It will be published here after verification.

Frequently Asked Questions

How to purchase chemical compound L127-0557?
Check Price and Availability of L127-0557, then you can add required amount to the Shopping Cart. In the Shopping Cart you can again refine your selection. Once you are sure that it’s exactly what you want you can move forward with the Checkout (to pay online by credit card, or via PayPal), or Request a Quote.
What is the minimum amount of L127-0557 you sell to drug discovery company or institution?
Available from 1 mg in Glass Vials or 96-tube racks.
Delivery options for L127-0557
ChemDiv sends parcels with Express services (UPS, WC).
  • 1–2 days for small orders
  • 2–4 weeks for large selections
Delivery formats for L127-0557
  • 0.5–50 mg of dry powder sample in single glass vials, custom vials
  • DMSO solutions frozen 10μl–250μl@10mM (96 and 384 format)

Custom synthesis of L127-0557 available by request